Results 111 to 120 of about 41,675 (262)

Evaluation of the Effects of Interfering Factors on the Bacterial Endotoxin Testing of Radiopharmaceuticals

open access: yesKorean Journal of Clinical Laboratory Science
The endotoxin test is based on the reaction between Limulus Amebocyte Lysate (LAL) and the lipopolysaccharides of Gram-negative bacteria. In this study, we sought to identify factors that interfere with the LAL testing of radiopharmaceuticals and ...
Jun Young PARK
doaj   +1 more source

Measurement of endotoxins in bioaerosols at workplace : a critical review of literature and a standardization issue

open access: yes, 2012
Endotoxins are lipopolysaccharides found in the outer membrane of most Gram-negative bacteria and cyanobacteria. Worker exposure to endotoxins has been shown in a number of work situations and is associated with both respiratory and systemic pathologies.
Duquenne, Phillipe   +3 more
core   +1 more source

Glycoengineered Recombinant Alpha1‐Antitrypsin Results in Comparable In Vitro and In Vivo Activities to Human Plasma‐Derived Protein

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Alpha‐1‐antitrypsin (A1AT) is a multifunctional, clinically important, high‐value therapeutic glycoprotein that can be used for the treatment of many diseases, such as A1AT deficiency, diabetes, graft‐versus‐host disease, cystic fibrosis, and various viral infections. Currently, the only U.S. food and drug administration‐approved treatment for
Frances Rocamora   +12 more
wiley   +1 more source

Sterilization Method for Borosilicate Glass Vials and Chlorobutyl, Bromobutyl Rubbers for Medical Purposes

open access: yesEurasian Chemico-Technological Journal
For surgical and medical tools to prevent the spreading of infectious microorganisms to patients, disinfection and sterilization must be achieved by the use of disinfectants and sterilization procedures.
I.S. Karapetyan, H.R. Petrosyan
doaj   +1 more source

Microbial Hydrolysates as Amino Acid Source in Cell Culture Media for Cellular Agriculture

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The high cost of cultivation media remains one of the barriers to the commercialization of cultivated meat. Current serum‐free media reduce reliance on fetal bovine serum but only achieve modest cost savings. Especially at larger scales (> 20 m3), pharmaceutical‐grade amino acids and recombinant proteins remain major cost drivers.
Jelle C. Hoek   +3 more
wiley   +1 more source

The level of endotoxins in hemodialysis water and dialysate

open access: yes, 2007
Hemodialysis is a process when the blood of patients contacts with dialysate through a semipermeable membrane. Water used for dialysis is not sterile.
Skarupskienė, Inga   +2 more
core  

Protein hydrolysates in cell culture: Toward multi‐omics characterization

open access: yesBiotechnology Progress, EarlyView.
While protein hydrolysates are widely used in cell culture applications, they remain undefined and variable products. Multi‐omic characterization evaluating composition and function can transition hydrolysates toward semi‐defined media components.
Michelle Combe   +3 more
wiley   +1 more source

Statistical Analysis of Cultural Parameters Influencing Delta-Endotoxins and Proteases Productions by Bacillus thuringiensis kurstaki

open access: yes, 2016
Bacillus thuringiensis is a spore-forming bacterium that produces delta-endotoxins, which are toxic to lepidopterans, dipterans and coleopterans. Concomitantly with production of delta-endotoxins, B.
Ben Hassen, Hanen   +2 more
core   +1 more source

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović   +11 more
wiley   +1 more source

Determination of endotoxins in the vital pulp of human carious teeth: Association with pulpal pain

open access: yes, 2001
Objectives. The aims of this investigation were to determine the presence or absence of endotoxins in the pulp of symptomatic and symptom-free human carious teeth, to quantify the amount of endotoxins present, and to associate the presence of endotoxins ...
Khabbaz, M.G.   +2 more
core  

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