Results 181 to 190 of about 64,600 (289)

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu   +5 more
wiley   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang   +5 more
wiley   +1 more source

Bacillus thuringiensis and its pest control potential as endophyte

open access: yesPest Management Science, EarlyView.
Bacillus thuringiensis (Bt) systemically colonizes tomato plants as endophyte, inducing midgut damage, fitness reduction and immune suppression in Spodoptera littoralis larvae feeding on Bt‐colonized leaves. The immune suppression enhances the susceptibility to Bt treatments, allowing a synergistic dual use of Bt commercial formulations, by combined ...
Maria Giovanna De Luca   +8 more
wiley   +1 more source

The scale matters: A review on stimuli‐responsive microrobots categorized by scale for biomedical applications

open access: yesResponsive Materials, EarlyView.
We systematically summarize how each scale dictates fundamental choices in design feature, manufacturing technology, driving mechanism, and control strategy, which are inherently governed by scale‐dominated physical principles. Furthermore, the application of scale‐determined operation modes of microrobots across different stages of medical ...
Hang Yin   +3 more
wiley   +1 more source

Validation of the Monocyte Activation Test Demonstrating Equivalence to the Rabbit Pyrogen Test. [PDF]

open access: yesInt J Mol Sci
Burgmaier L   +5 more
europepmc   +1 more source

A UAV‐based deep learning pipeline for intertidal macrobenthos monitoring: Behavioral and age classification in Tachypleus tridentatus

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
The endangered tri‐spine horseshoe crab (Tachypleus tridentatus), a “living fossil” crucial to coastal ecology and biomedical research, is experiencing severe population declines. Effective conservation requires efficient monitoring, which traditional methods cannot deliver at scale. We develop an integrated UAV deep learning framework tailored to this
Xiaohai Chen   +7 more
wiley   +1 more source

Robust Bioconjugated Antigens Induce Immune Responses Preventing Malaria Infection and its Transmission

open access: yesSmall, EarlyView.
Engineered malaria antigens enable in vivo bioconjugation to submicron biopolymer particles in E. coli. Two antigens are co‐tethered at high density and defined stoichiometry. The resulting thermostable particles elicit strong, durable antibody and T‐cell responses, conferring robust protection and blocking mosquito transmission.
Nivethika Sivakumaran   +10 more
wiley   +1 more source

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