Comment on "Dietary dimethylglycine alleviates cyclic heat stress-induced jejunal injury in yellow-feathered broilers by inhibiting the TLR4/NF-κB signaling pathway and restoring MUC2 expression". [PDF]
Poult SciSati DM, Shinde VD, Agarwal C.
europepmc +1 more source
Toll‐like receptor 4 mediates lipopolysaccharide‐induced emesis
British Journal of Pharmacology, EarlyView.Background and Purpose Lipopolysaccharide (LPS) induces inflammation and sepsis through Toll‐like receptor 4 (TLR4) activation. Common laboratory animals do not exhibit emesis, but administration of LPS in piglets, cats, and dogs induces emesis via peripheral mechanisms.
Luping Liu +5 more
wiley +1 more source
Assessment of the Microcirculation During Extracorporeal Blood Purification in Septic Patients: A Narrative Review. [PDF]
Medicina (Kaunas)Smirnova D, Klibus M, Sabelnikovs O.
europepmc +1 more source
Cell Proliferation, EarlyView.Clinical‐grade HLA‐homozygous iPSC‐derived neural precursor cells restore motor function, rebuild striatal circuitry and reduce neuroinflammation in QA‐lesioned rats. These findings demonstrate robust neuronal replacement and microenvironment modulation, supporting their potential as a regenerative therapy for Huntington's disease.
Hyeonjoong Jeon +6 more
wiley +1 more source
An Engineered Solidified Peptide Hemocyte Sponge as Nanomotor Storage to Combat Bacterial Colitis. [PDF]
Adv Sci (Weinh)Fang Y +8 more
europepmc +1 more source
Human Pancreatic Cancer Organoids
Cell Proliferation, EarlyView.This guideline establishes a comprehensive framework for the application of patient‐derived pancreatic cancer organoids. It outlines the stringent technical requirements and testing methods necessary to ensure high fidelity to the original tumor tissue, including morphological assessment, pathological biomarker expression (e.g., CK19, CK7), and genetic
Aina He +44 more
wiley +1 more source
Monocytes Derived From Human Pluripotent Stem Cells Engineered for Detection of Pyrogens
Cell Proliferation, EarlyView.In summary, we have developed a monocyte‐based reporter system using hESC‐Mono for interrogating the NF‐κB signalling axis, a central pathway governing pyrogenic responses. Our platform enables rapid and dose‐dependent detection of both endotoxins (LPS) and non‐endotoxins (LTA and Zymosan).
Jingjing Liu +8 more
wiley +1 more source
The role of gut microbiota in the onset and development of sepsis and its therapeutic potential: mechanisms and research progress. [PDF]
Front MicrobiolTian Z, Li C.
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Nematode in Cockroaches: A Potential Allergen Source
Allergy, EarlyView.
Dongjun Kang +5 more
wiley +1 more source
Cell Proliferation, EarlyView.Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao +7 more
wiley +1 more source