Results 41 to 50 of about 454,673 (312)

Managing Endowment Fund Income in Universities

open access: yesВопросы образования, 2016
In this paper, we discuss the methods of endowment management existing in the world and their applicability to the Russian university system. The endowment spending research focuses on the following issues: reinvesting endowment income; identifying the ...
Elza Dyachkova
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Government’s supervision on endowments: study on challenges of receiving observer’s fee from endowments by endowment and charity affairs organization [PDF]

open access: yesFaṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī, 2017
: management of Public endowment affairs without a trustee or an unknown one and private endowment have been delegated to endowment and charity affairs organization under certain conditions.
Keyvan Sedaghati, Mohammad Jalali
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Early Scholars' Visits to Central America: Reports by Karl Sapper, Walter Lehmann, and Franz Termer, edited by Marilyn Beaudry-Corbett and Ellen T Hardy, Theodore E Gutman, 2000

open access: yesBulletin of the History of Archaeology, 2001
The Cotsen Institute's Director of Publications is archaeologist Marilyn Beaudry-Corbett, herself a specialist on the production and distribution of archaeological ceramics in Mesoamerica and Central America and a scholar of ...
Charles C. Kolb
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Toward a Social History ofArchaeology in the United States, by Thomas C. Patterson. Harcourt Brace College Publishers, Fort Worth, 1995

open access: yesBulletin of the History of Archaeology, 1997
This volume, one of the initial publications in the Harcourt Brace "Case Studies in Archaeology" series edited by Jeffrey Quilter, is designed, the editor writes, for broad appeal as an inexpensive textbook for students enrolled ...
Charles C. Kolb
doaj   +1 more source

The Role of Endowments in Financial Markets: Key Trends in 1990-2020 in the USA (on the example of the US education sector)

open access: yesМир новой экономики, 2021
This article describes the key trends in the development of endowments as institutional investors using the example of US educational endowments in 1990-2020.
K. B. Bakhtaraeva
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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