Results 51 to 60 of about 141,604 (290)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Erzurum Caferiye Mosque and Its Calligraphies
Art TimeIslamic calligraphy, an important part of the rich artistic and cultural heritage of Islamic civilization, has not only conveyed the content of the text but also served to convey messages with deep meaning to its addressee through an aesthetic language ...
Yunus Berkli, Betül Akgönül Yıldız
doaj +1 more source
Bulletin of the History of Archaeology, 1997 This volume, one of the initial publications in the Harcourt Brace "Case Studies in Archaeology" series edited by Jeffrey Quilter, is designed, the editor writes, for broad appeal as an inexpensive textbook for students enrolled ...
Charles C. Kolb
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Government’s supervision on endowments: study on challenges of receiving observer’s fee from endowments by endowment and charity affairs organization [PDF]
Faṣlnāmah-i Pizhūhish-i Huqūq-i ̒Umūmī, 2017 : management of Public endowment affairs without a trustee or an unknown one and private endowment have been delegated to endowment and charity affairs organization under certain conditions.
Keyvan Sedaghati, Mohammad Jalali
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Bulletin of the History of Archaeology, 1997 What might Friedrich Nietzsche, Ludwig Wittgenstein, Jacques Derrida, Anthony Giddens, Claude Levi Strauss, Louis Binford, Michael Shanks, and Daniel Miller have in common? What are the relationships between McGuire's A Marxist
Charles C. Kolb
doaj +1 more source
The endowment effect in games [PDF]
European Economic Review, 2015 In a laboratory experiment we study whether the endowment effect exists in a social and strategic context. We employ a within-subjects design whereby participants are asked for their Willingness-to-Accept (WTA) or Willingness-to-Pay (WTP) to play a series of 2x2 games.
Michalis Drouvelis, Joep Sonnemans
openaire +5 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Bulletin of the History of Archaeology, 1999 Human sacrifice and cannibalism, the potential for institutionalized violence or warfare, witchcraft or sorcery, and ritual executions are emotionally charged issues; but some anthropologists and other learned scholars now
Charles C. Kolb
doaj +1 more source