Results 131 to 140 of about 2,705,124 (338)
Chest Radiographs for Pediatric TB Diagnosis: Interrater Agreement and Utility
Interdisciplinary Perspectives on Infectious Diseases, 2014 The chest radiograph (CXR) is considered a key diagnostic tool for pediatric tuberculosis (TB) in clinical management and endpoint determination in TB vaccine trials. We set out to compare interrater agreement for TB diagnosis in western Kenya.
G. Kaguthi +5 more
doaj +1 more source
Mixing It Up With MT2: Unbiased Mass Measurements at Hadron Colliders
, 2011 Recently, much progress has been made on techniques to measure the masses of new particles with partially-invisible decays at a hadron collider. We examine for the first time the realistic application of MT2-based measurement methods to a fully hadronic ...
Curtin, David
core +1 more source
The Feynman Trajectories: Determining the Path of a Protein Using Fixed-Endpoint Assays [PDF]
SLAS Discovery, 2010 Richard Feynman postulated in 1948 that the path of an electron can be best described by the sum or functional integral of all possible trajectories rather than by the notion of a single, unique trajectory. As a consequence, the position of an electron does not harbor any information about the paths that contributed to this position.
openaire +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Measurement of the Superparticle Mass Spectrum in the Long-Lived Stau Scenario at the LHC
, 2009 In supersymmetric scenarios with a long-lived stau, the LHC experiments provide us with a great environment for precise mass measurements of superparticles.
A Nisati +23 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Detecting kinematic boundary surfaces in phase space: particle mass measurements in SUSY-like events
Journal of High Energy Physics, 2017 We critically examine the classic endpoint method for particle mass determination, focusing on difficult corners of parameter space, where some of the measurements are not independent, while others are adversely affected by the experimental resolution ...
Dipsikha Debnath +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Determination of Cause of Death Among Breast Cancer Cases in the Swedish Randomized Mammography Screening Trials: A comparison between official statistics and validation by an endpoint committee [PDF]
, 1995 Lennarth Nyström +10 more
openalex +1 more source
Hadronic Spectrum in Inclusive Semileptonic B Decays
, 1994 We evaluate the inclusive semileptonic B decay spectrum as a function of the final-state hadrons energy to second order in the inverse quark mass expansion and tree level in $\alpha_{s}$. We argue that there is an energy interval below the $c$ production
Antonio O. Bouzas +8 more
core +2 more sources