Results 221 to 230 of about 2,705,124 (338)

FDA-AACR Strategies for Optimizing Dosages for Oncology Drug Products: Early-Phase Trials Using Innovative Trial Designs and Biomarkers. [PDF]

Clin Cancer Res
Okusanya OO, Patilea-Vrana GI, Sireci A, Iasonos A, Davidson BA, Liu J, Shord SS, LoRusso PM, Yap TA.   +8 more
europepmc   +1 more source

Determination of relevant endpoints to evaluate the in vivo barrier function in cutaneous health

, 2019
Emília Alves, Patrícia Ríjo, Luís Monteiro Rodrigues, Catarina Rosado   +3 more
openalex   +1 more source

Influence of Incubation Time, Inoculum Size, and Glucose Concentrations on Spectrophotometric Endpoint Determinations for Amphotericin B, Fluconazole, and Itraconazole [PDF]

, 1999
M. Hong Nguyen, Christine Yu
openalex   +1 more source

Testing A Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans

Arthritis Care &Research, Accepted Article.
Objective We aimed to test the efficacy of personalized treatment of older Veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABC) as compared with usual care (UC). Methods Two hundred ninety‐nine Veterans age 65‐89 with CLBP from 3 VA medical centers underwent baseline testing, randomization to ABC or UC and 12 months follow ...
Debra K. Weiner, Angela Gentili, Meika A. Fang, Edward Garay, Laura Lawson, Lenore Joseph, Cathy C. Lee, Michelle I. Rossi, Beverly Thorn, Subashan Perera   +9 more
wiley   +1 more source

Effect of a Dihydroxyacetone-Based Camouflage Agent on Ultraviolet-Induced Erythema. [PDF]

J Cosmet Dermatol
Shu D, Han Y, Chen D, Li Z, Zhao Y.
europepmc   +1 more source

A spectrophotometric evaluation of one non-iron and three iron type reactions used for the endpoint determination of serum cholesterol.

, 1977
Joseph D. Artiss
openalex   +2 more sources

Digital Behavioral Therapy Improves Outcome in Patients With Axial Spondyloarthritis and Persistent Pain: A Randomized Controlled Trial

Arthritis Care &Research, EarlyView.
Objective Axial spondyloarthritis (axSpA) is often associated with persistent pain despite effective anti‐inflammatory treatment. Digital health applications (DHAs) provide innovative approaches to address multidimensional aspects of persistent pain through psychological and behavioral strategies. The aim of this study was to assess the impact of a DHA
David Kiefer, Yade Sonkaya, Dietmar Krause, Markus Voglau, Bernhard Mintrop, Imke Redeker, Xenofon Baraliakos, Uta Kiltz   +7 more
wiley   +1 more source

Group-Sequential Designs With an Externally-Driven Change of Primary Endpoint. [PDF]

Stat Med
Yarahmadi A, Dodd LE, Horby P, Jaki T, Stallard N.   +4 more
europepmc   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Has FDA's Drug Development Tools Qualification Program Improved Drug Development? [PDF]

Ther Innov Regul Sci
Yang F, Bousnina I, Madej A, Kalamegham R.   +3 more
europepmc   +1 more source