Results 31 to 40 of about 1,860,209 (301)

RADAR-base/radar-helm-charts: radar-push-endpoint-0.2.2

open access: yes, 2023
<p>A Helm chart for RADAR-base Push Endpoint. REST Gateway to Kafka, for incoming data from Push or Subscription based WEB APIs. It performs authentication, authorization and content validation.
Joris Borgdorff   +4 more
core   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga   +3 more
wiley   +1 more source

Choosing primary endpoints for clinical trials of health care interventions

open access: yesContemporary Clinical Trials Communications, 2019
The purpose of late phase clinical trials is to generate evidence of sufficient validity and generalisability to be translated into practice and policy to improve health outcomes.
Charlie McLeod   +5 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

State, Security, and Economy in Afghanistan: Current Challenges, Possible Solutions

open access: yes, 2007
Recommendations in this report address three broad issue areas key to ongoing state- and security-building efforts in Afghanistan: political reform, regional relationships, and international priorities.
Liechtenstein Institute on Self-Determination
core   +1 more source

Sotorasib in KRASG12C mutated lung cancer: Can we rule out cracking KRAS led to worse overall survival?

open access: yesTranslational Oncology, 2023
The KRAS oncogene is present in up to 25% of solid tumors and for decades had been undruggable. Sotorasib was the first-in-class KRAS inhibitor to reach the US and European market, and its pharmacological inhibition is restricted to the KRAS p.G12C ...
Timothée Olivier   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Iran, Its Nuclear Ambitions, the Region, and the West

open access: yes, 2006
The report addresses the ongoing Iranian nuclear crisis and related policy issues, Iran’s nuclear aspirations based on the internal politics of the country, Iran’s interstate relations and the role it occupies within the Middle East and Central Asia, and
Liechtenstein Institute on Self-Determination
core   +1 more source

Uncertainty-aware IoT-based moisture monitoring and endpoint control for banana drying in a parabolic solar dryer

open access: yesJournal of Agriculture and Food Research
This study developed an uncertainty-aware Internet of Things (IoT)-based framework for real-time moisture monitoring and endpoint determination during banana drying in a parabolic solar dryer.
Narathip Sujinda, Sasitorn Nakthong
doaj   +1 more source

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