Results 51 to 60 of about 73,823 (281)

Application of a Novel Colour Palette for Determination of End-point Decalcification of Hard Tissues: A Cross-sectional Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Decalcification is a technique used to remove calcium salts from hard tissue specimens, such as bone or teeth, to make them suitable for sectioning.
N Fazulunnisa Begum   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Clinical and biomarker endpoint analysis in neoadjuvant endocrine therapy trials

open access: yes, 2005
Neoadjuvant endocrine therapy trials for breast cancer are now a widely accepted investigational approach for oncology cooperative group and pharmaceutical company research programs.
Tao, Yu   +4 more
core   +1 more source

Searching for the QCD critical point through constant entropy density contours [PDF]

open access: yesEPJ Web of Conferences
We propose a novel method to locate the QCD critical point by constructing an expansion along contours of constant entropy density. Applying two independent analyses of lattice QCD data at zero baryon chemical potential, we find a critical point at Tc ...
Shah Hitansh   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Measurement of masses in the t(t)over-bar system by kinematic endpoints in pp collisions at √s=7 TeV [PDF]

open access: yes, 2013
This article is the pre-print version of the final published paper that is available from the link below.A simultaneous measurement of the top-quark, W-boson, and neutrino masses is reported for tt events selected in the dilepton final state from a data ...
Pape, L   +999 more
core   +1 more source

Alternative methods for top-quark mass determination at the Tevatron and LHC

open access: yes, 2013
I am summarizing here the determination of the top-quark mass from the CDF and D0 Collaborations at the Tevatron and the ATLAS and CMS Collaborations at the LHC using non-conventional methods.
Déliot, Frédéric
core   +2 more sources

PREDICTION AND DIAGNOSIS OF SPORADIC MULTIGLANDULAR PARATHYROID DISEASE BY THE METHOD OF MATHEMATICAL ANALYSIS

open access: yesБайкальский медицинский журнал, 2022
Background. Sporadic multiglandular parathyroid disease remains an unresolved problem in endocrine surgery. This is due to the complexity of clinical and laboratory prediction, insufficient sensitivity of imaging methods and intraoperative monitoring of ...
E.A. Ilyicheva, G.A. Bersenev
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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