Results 41 to 50 of about 48,219 (257)

Research progress on the synthesis of energetic N-oxides based on diazine, triazine and tetrazine

FirePhysChem
The skeleton structures of azine (including diazine, triazine and tetrazine) are widely used as important candidate for building good performance energetic materials due to their uniform electron distribution, planar aromaticity, multi reactive sites and
Jiarong Zhang, Huan Huo, Lianjie Zhai, Fuqiang Bi, Bozhou Wang   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Sensitive Energetics from the N‐Amination of 4‐Nitro‐1,2,3‐Triazole

ChemistryOpen, 2020
Energetic N‐amino‐C‐nitro compounds 1‐amino‐4‐nitro‐1,2,3‐triazole and 2‐amino‐4‐nitro‐1,2,3‐triazole are characterized for the first time as energetic materials. These compounds were characterized chemically by nuclear magnetic resonance (NMR), Infrared
Dominique R. Wozniak, Benjamin Salfer, Dr. Matthias Zeller, Dr. Edward F. C. Byrd, Prof. Davin G. Piercey   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Military High Explosives

CHIMIA, 2004
Military high explosives are safe to handle, have a long shelf life, their energy density is high and the propagation of the explosion (detonation reaction) is very fast. The energetic compounds are combined with polymers and other substances to
Jörg Mathieu, Hans Stucki
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Energetics of hydrogen bonding in proteins: A model compound study [PDF]

Protein Science, 1996
AbstractDifferences in the energetics of amide‐amide and amide‐hydroxyl hydrogen bonds in proteins have been explored from the effect of hydroxyl groups on the structure and dissolution energetics of a series of crystalline cyclic dipeptides. The calorimetrically determined energetics are interpreted in light of the crystal structures of the studied ...
S M, Habermann, K P, Murphy
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A comparative study of bridged 1,2,4-oxazolones and their derivatives

Energetic Materials Frontiers, 2020
For energetic compounds, a slight difference in their molecular structures can result in a tremendous difference in their properties. Compounds with similar structures but exhibiting big difference in their physicochemical properties (such as density and
Teng Fei, Chenghui Sun, Chunlin He, Siping Pang   +3 more
doaj   +1 more source

Bonding Energetics in Organometallic Compounds [PDF]

, 1990
The acquisition, analysis, and understanding of metal-ligand bond energy information in organometallic molecules is an active and important area of chemical research. This new volume presents a broad, up-to-date, and in-depth overview of the current state of knowledge in this field.
openaire   +1 more source