Results 111 to 120 of about 882,651 (290)

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Extended pan-spectrum fitting of energetic particle spectra

Earth and Planetary Physics
The energy spectrum of energetic particles in space often shows a non-thermal spectral shape with two spectral transitions/breaks over a wide energy range, carrying crucial information about their acceleration, release and transportation process. To self-
WenYan Li, LingHua Wang, YongFu Wang, XinNian Guo, QianYi Ma   +4 more
doaj   +1 more source

Accélération non adiabatique des ions causée par des ondes électromagnétiques (observations de Cluster et Double Star) et réponse du champ géomagnétique aux variations de la pression dynamique du vent solaire [PDF]

, 2013
Cette thèse comporte deux thèmes principaux: l'un concerne l'accélération non adiabatique des ions dans la couche de plasma proche de la Terre, l'autre les pulsations géomagnétiques dues à la décroissance de la pression dynamique du vent solaire.
Wang, Zhiqiang
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Influence of sawtooth oscillations on fast ions in a stellarator

Nuclear Fusion
Sawtooth oscillations in tokamaks frequently lead to the redistribution of energetic ions, mainly on passing orbits, causing their expulsion from the core.
D. Moseev, M. Zanini, H. Kasahara, H.P. Laqua, H. Funaba, W.H.J. Hayashi, W. Heidbrink, K. Ida, H. Igami, Y. Kawamoto, N. Kenmochi, S.A. Lazerson, M. Nishiura, R. Ochoukov, K. Ogawa, M. Rud, M. Salewski, T. Seki, N. Tamura, K. Tanaka, T. Tokuzawa, M. Yoshinuma   +21 more
doaj   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

The Energetic Oxygen Ion Beams in the Martian Magnetotail Current Sheets: Hints From the Comparisons Between Two Types of Current Sheets

Geophysical Research Letters
Using data from the Mars Atmosphere and Volatile EvolutioN (MAVEN) mission, we explore the plasma properties of Martian magnetotail current sheets (CS), to further understand the solar wind interaction with Mars and ion escape.
Chi Zhang, Zhaojin Rong, Xinzhou Li, Markus Fränz, Hans Nilsson, Riku Jarvinen, Moa Persson, Yoshifumi Futaana, Chuanfei Dong, Masatoshi Yamauchi, Jiawei Gao, Yijia Zhou, Lei Wang, Zhen Shi, Yong Wei, Fei He, Mats Holmström, Stas Barabash   +17 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source