Results 51 to 60 of about 5,733,113 (297)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Improved printing of energetic materials

open access: yes, 2020
The invention is directed to a method for the preparation of an energetic material product such as a propellant or explosive charge or grain, wherein said method comprises additive manufacturing comprising co-extrusion of at least two materials to form a
Bommel, K.J.C.   +2 more
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Propellant charge or grain with printed energetic material layers

open access: yes, 2020
Propellant charges or grains having printed layers of two or more energetic materials are described along with methods for preparing and using ...
Straathof, M.H., Driel, C.A. van
core  

Nanometals in energetic systems: Achievements and future

open access: yes, 2022
S.399-419The characterization of nanometals that are mostly produced by electrical explosion of wires and a comprehensive survey of their usage in different energetic systems are presented.
DeLuca, L.T.   +5 more
core   +1 more source

Crystal structure of 3,3′-biisoxazole-5,5′-bis(methylene) dinitrate (BIDN)

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2017
The molecular structure of the title energetic compound, C8H6N4O8, is composed of two planar isoxazole rings and two near planar alkyl-nitrate groups (r.m.s deviation = 0.006 Å).
Rosario C. Sausa   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ti/CuO and Ti/CuO/Cellulose Nitrate Nanothermites: An Early Insight into Their Combustion Mechanism

open access: yesEnergies
Most nanothermite compositions utilise Al as a fuel, due to its low cost, high reactivity and availability. Nevertheless, aluminothermites exhibit high ignition temperature and low active metal content.
Mateusz Polis   +8 more
doaj   +1 more source

Determination of the HMX and RDX content in synthesized energetic material by HPLC, FT-MIR, and FT-NIR spectroscopies

open access: yesQuímica Nova, 2004
A new method has been developed for determining the content of mixtures of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), the HMX/RDX ratio, in explosive compositions by Fourier transform ...
Elizabeth C. Mattos   +5 more
doaj   +1 more source

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