Results 51 to 60 of about 5,733,113 (297)
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Improved printing of energetic materials
The invention is directed to a method for the preparation of an energetic material product such as a propellant or explosive charge or grain, wherein said method comprises additive manufacturing comprising co-extrusion of at least two materials to form a
Bommel, K.J.C. +2 more
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Propellant charge or grain with printed energetic material layers
Propellant charges or grains having printed layers of two or more energetic materials are described along with methods for preparing and using ...
Straathof, M.H., Driel, C.A. van
core
Nanometals in energetic systems: Achievements and future
S.399-419The characterization of nanometals that are mostly produced by electrical explosion of wires and a comprehensive survey of their usage in different energetic systems are presented.
DeLuca, L.T. +5 more
core +1 more source
Crystal structure of 3,3′-biisoxazole-5,5′-bis(methylene) dinitrate (BIDN)
The molecular structure of the title energetic compound, C8H6N4O8, is composed of two planar isoxazole rings and two near planar alkyl-nitrate groups (r.m.s deviation = 0.006 Å).
Rosario C. Sausa +4 more
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ti/CuO and Ti/CuO/Cellulose Nitrate Nanothermites: An Early Insight into Their Combustion Mechanism
Most nanothermite compositions utilise Al as a fuel, due to its low cost, high reactivity and availability. Nevertheless, aluminothermites exhibit high ignition temperature and low active metal content.
Mateusz Polis +8 more
doaj +1 more source
A new method has been developed for determining the content of mixtures of octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX) and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), the HMX/RDX ratio, in explosive compositions by Fourier transform ...
Elizabeth C. Mattos +5 more
doaj +1 more source

