Results 41 to 50 of about 96,375 (265)

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Pyrolysis mechanism and evolved gas analysis of a promising energetic carbamate-functionalized microcrystalline cellulose nitrate

FirePhysChem
The present study aims to elucidate the decomposition mechanism and gas evolution characteristics of a promising energy-rich carbamated microcrystalline cellulose nitrate (M3CN).
Hani Boukeciat, Ahmed Fouzi Tarchoun, Djalal Trache, Amir Abdelaziz, Djamal Belmehdi, Redha Meziani, Lokmene Boumaza, Thomas M. Klapötke   +7 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Unraveling the role of ammonium perchlorate on the thermal properties and degradation kinetics of NPS-DEGDN energetic composite

FirePhysChem
Double-base energetic composites have garnered substantial attention, particularly in aerospace, rocket, and missile applications. This class of materials offers diverse burning rates, high specific impulses, exceptional operational performance, and ...
Nassima Sahnoun, Amir Abdelaziz, Memdouh Chebbah, Ahmed Fouzi Tarchoun, Hani Boukeciat, Yash Pal, Weiqiang Pang, Djalal Trache   +7 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Exploring the effect of ammonium nitrate on the thermal stability and decomposition kinetics of dual nitrocellulose-nitrostarch-based energetic composites

FirePhysChem
This study explores a dual-biopolymer-based energetic composite, emphasizing the synergistic effects achieved by combining nitrocellulose (NC) and nitrostarch (NPS) biopolymers with ammonium nitrate (AN), as an oxidizer.
Nawel Matmat, Amir Abdelaziz, Ahmed Fouzi Tarchoun, Hani Boukeciat, Mohammed Jouini, Fateh Chalghoum, Djalal Trache   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Enhancing energetic features of HTPB binder through nitro-functionalization and nitrocellulose doping

FirePhysChem
This study presents a double modification strategy to enhance hydroxyl‑terminated polybutadiene (HTPB) properties as an energetic binder. HTPB was chemically nitrated to obtain nitro-HTPB (NHTPB), then blended with nitrocellulose (NC) at different ratios
Mohammed Jouini, Amir Abdelaziz, Ahmed Fouzi Tarchoun, Fathi Rahamnia, Slimane Bekhouche, Yash Pal, Weiqiang Pang, Djalal Trache   +7 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Exploring the effect of kraft lignin on the stability and decomposition kinetics of nitrated cellulose carbamate

FirePhysChem
This study systematically investigated the stability and thermo-kinetic properties of a high-energy-density nitrated cellulose carbamate (NCC) system stabilized with Kraft lignin.
Lokmene Boumaza, Ahmed Fouzi Tarchoun, Amir Abdelaziz, Yacine Yahi, Nabil Slimani, Chemseddine Boustila, Mohammed Jouini, Thomas M. Klapötke, Weiqiang Pang, Djalal Trache   +9 more
doaj   +1 more source