Results 61 to 70 of about 29,430 (259)

Energetic Particle Observations at Synchronous Orbit : Multiple-Satellite Study for Flux Variation by GOES-2, GOES-3 and GMS and Nightside Flux Depression for Continuous Geomagnetic Activity by GMS (a. Precipitating Particles and Auroras) (Proceedings of the Second Symposium on Coordinated Observations of the Ionosphere and Magnetosphere in the Polar Regions : Part I)

Antarctic Record, 1980
This article reports the results of studying the behavior of the energetic particle flux obtained at synchronous orbit during substorms. The multi-satellite study has clearly showed that the evening particle flux decrease contrasts with the behavior in ...
Tsugunobu NAGAI, Tsuyoshi KOHNO
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Acceleration and Propagation of Solar Energetic Particles [PDF]

Space Science Reviews, 2017
Solar Energetic Particles (SEPs) are an important component of Space Weather, including radiation hazard to humans and electronic equipment, and the ionisation of the Earth's atmosphere. We review the key observations of SEPs, our current understanding of their acceleration and transport, and discuss how this knowledge is incorporated within Space ...
Klein, Karl-Ludwig, Dalla, Silvia
openaire   +3 more sources

Hybrid simulations of fishbones with high order harmonics in EAST Tokamak

Nuclear Fusion
The linear stability and nonlinear dynamics of fishbones with high order harmonics have been investigated by the global kinetic-magnetohydrodynamic (MHD) code M3D-K in the Experimental Advanced Superconducting Tokamak (EAST).
Shengfa Wu, Wei Shen, Zhiyong Qiu, Liqing Xu   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Numerical investigation of particle acceleration at interplanetary shocks: Diffusive and superdiffusive scenarios

Astronomy & Astrophysics
Context. Energetic particles are ubiquitous in space and astrophysical plasmas, and interplanetary shocks are widely regarded as one of the main particle accelerators in the heliosphere. Indeed, in situ measurements typically show that energetic particle
Prete G., Zimbardo G., Perri S.
doaj   +1 more source

The Electron Proton Helium INstrument as an example for a Space Weather Radiation Instrument

Journal of Space Weather and Space Climate, 2020
The near-Earth energetic particle environment has been monitored since the 1970’s. With the increasing importance of quantifying the radiation risk for, e.g.
Kühl Patrick, Heber Bernd, Gómez-Herrero Raúl, Malandraki Olga, Posner Arik, Sierks Holger   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source