Results 91 to 100 of about 4,526,063 (300)
Design of an interplanetary ultralow-noise three-dimensional energetic particle spectrometer
地球与行星物理论评The origin and acceleration of solar and heliospheric energetic particles have been prevalent research frontiers in space physics. Solar and heliospheric energetic particles measured in the interplanetary medium (IPM) can be classified into two major ...
Xiangqian Yu +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
ATEP: an advanced transport model for energetic particles
Nuclear FusionIn this paper we report on the implementation and verification of a phase-space resolved energetic particle (EP) transport model. It is based on a first-principle theoretical framework, i.e.
Ph. Lauber +6 more
doaj +1 more source
Detection of lower tropospheric responses to solar energetic particles at midlatitudes.
Physical Review Letters, 2014 Solar energetic particles (SEPs) occasionally contribute additional atmospheric ionization beyond that arising from the usual galactic cosmic ray background.
K. Nicoll, R. Harrison
semanticscholar +1 more source
The Two Sources of Solar Energetic Particles [PDF]
, 2012 Evidence for two different physical mechanisms for acceleration of solar energetic particles (SEPs) arose 50 years ago with radio observations of type III bursts, produced by outward streaming electrons, and type II bursts from coronal and interplanetary
D. Reames
semanticscholar +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Energetic Particles from Quasi-separatrix Layers and Current Sheets at the Sun
The Astrophysical JournalQuasi-separatrix layers (QSLs) at the Sun are created in regions where channels of open magnetic flux have footpoints near regions of large-scale closed magnetic flux. These regions show rapid changes in curvature and field strength.
Nathan A. Schwadron +4 more
doaj +1 more source
, 2017 Diseño térmico del instrumento EPE (Energetic Particles ...
González-Llana de los Reyes, Arturo
core
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Nuclear FusionThe capability of the global, electromagnetic gyrokinetic GENE code interfaced with the transport Tango solver is exploited to address the impact of fusion alpha particles (in their dual role of fast particles and heating source) on plasma profiles and ...
A. Di Siena +17 more
doaj +1 more source