Results 31 to 40 of about 517,027 (264)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Crashworthiness behavior of fiberglass tube subjected to axial load

open access: yesKKU Engineering Journal, 2014
This research is purposed to study crashworthiness behavior of fiberglass tube subjected axial compression. The specimens are made of fiberglass and hand lay-up in different ply angles which are; specimen A ply angle is [(0/90)/(0/90)/(0/90)] specimen B ...
Visit Junchuan   +3 more
doaj  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Reliability Analysis of Collision Energy Absorption for Anti-climber Devices Based on Improved Sum of Sine Surrogate Model

open access: yesChengshi guidao jiaotong yanjiu
Objective To reasonably evaluate the energy absorption reliability index of anti-climber devices, a reliability analysis method based on ISSSM (improved sinusoidal and surrogate model) is proposed.
CAO Yang   +5 more
doaj   +1 more source

The Absorption of Energy in Condensers [PDF]

open access: yesPhysical Review (Series I), 1904
n ...
openaire   +2 more sources

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Semi-empirical relationship for the energy absorption buildup factor in some biological samples [PDF]

open access: yesNuclear Technology and Radiation Protection, 2016
Energy absorption buildup factors in the energy range of 0.2 MeV to 2 MeV using a geometric progression fitting approximation in some selected essential amino acids, fatty acids and carbohydrate molecules have been obtained.
Salehi Danial   +2 more
doaj   +1 more source

Sandwich Structures for Energy Absorption Applications: A Review [PDF]

open access: yesMaterials, 2021
It is crucial that proper engineering structures are designed as energy absorbers for high dynamic loading situations, such as accidents, blasts, or impacts. The role of such structures is to absorb the high kinetic energy as strain energy through irreversible deformation of the structure.
openaire   +4 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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