Results 31 to 40 of about 6,766,293 (292)
Quasi-static axial compression experiments were conducted on the composite thin-walled C-channels with different flange widths. The axial compression failure modes and failure mechanisms were analyzed through CT scanning,and the effects of different ...
MOU Haolei +4 more
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Estimation of the characteristic energy of electron precipitation [PDF]
International audienceData from simultaneous observations (on 13 February 1996, 9 November 1998, and 12 February 1999) with the IRIS, DASI and EISCAT systems are employed in the study of the energy distribution of the electron precipitation during ...
delPozo, C. F. +6 more
core +2 more sources
Coupler Energy Absorption Schemes for 4-vehicle Formation Coupled Metro Train
[Objective] The coupler buffer energy absorption system is a key part in the overall energy absorption system of metro trains, having significant influence on train safety and comfort.
DONG Yanbing
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The energy absorption structure of a train is an important part of passive safety protection during train collisions and is the last line of defense to protect both passengers and trains.
Weinian Guo +5 more
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Crashworthiness behavior of fiberglass tube subjected to axial load
This research is purposed to study crashworthiness behavior of fiberglass tube subjected axial compression. The specimens are made of fiberglass and hand lay-up in different ply angles which are; specimen A ply angle is [(0/90)/(0/90)/(0/90)] specimen B ...
Visit Junchuan +3 more
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