Results 41 to 50 of about 659,767 (315)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Crashworthiness optimization for cutting energy-absorbing structures based on the multiobjective G-CBW method

open access: yesAlexandria Engineering Journal, 2023
The energy absorption structure of a train is an important part of passive safety protection during train collisions and is the last line of defense to protect both passengers and trains.
Weinian Guo   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Crashworthiness behavior of fiberglass tube subjected to axial load

open access: yesKKU Engineering Journal, 2014
This research is purposed to study crashworthiness behavior of fiberglass tube subjected axial compression. The specimens are made of fiberglass and hand lay-up in different ply angles which are; specimen A ply angle is [(0/90)/(0/90)/(0/90)] specimen B ...
Visit Junchuan   +3 more
doaj  

Maximizing Terahertz Energy Absorption with MXene Absorber

open access: yesNano-Micro Letters, 2023
Highlights MXene film absorbers enable the near theoretical absorption strength in extremely wide wavebands of 0.5–10 THz.
Xinliang Li, Hao Luo
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Dynamic modelling and analysis of post-combustion CO2 chemical absorption process for coal-fired power plants [PDF]

open access: yes, 2010
Post-combustion capture by chemical absorption using MEA solvent remains the only commercial technology for large scale CO2 capture for coal-fired power plants.
Yeung, Hoi   +9 more
core   +1 more source

Reliability Analysis of Collision Energy Absorption for Anti-climber Devices Based on Improved Sum of Sine Surrogate Model

open access: yesChengshi guidao jiaotong yanjiu
Objective To reasonably evaluate the energy absorption reliability index of anti-climber devices, a reliability analysis method based on ISSSM (improved sinusoidal and surrogate model) is proposed.
CAO Yang   +5 more
doaj   +1 more source

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