Results 71 to 80 of about 659,767 (315)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Intestinal barrier function and absorption in pigs after waeaning: a review [PDF]

open access: yes, 2011
Under commercial conditions, weaning of piglets is associated with social, environmental and dietary stress. Consequently, small-intestinal barrier and absorptive functions deteriorate within a short time after weaning.
Wijtten, P.J.A.   +2 more
core   +1 more source

Energy absorption mode and mechanical matching of crashworthiness structure aheads for standardized metro train

open access: yes机车电传动, 2022
Lightweight and high specific energy absorption device is the key development component of standardized subway train. It is important to enhance the matching design of special energy absorption device to improve the crashworthiness of structure.
YANG Xiangyun, LU Zhaijun
doaj  

Energy Absorption and Propagation in Laser-Created Sparks [PDF]

open access: yesApplied Spectroscopy, 2004
The energy absorption and laser propagation characteristics of air and argon sparks at one atmosphere have been investigated. To create the sparks, 532 nm pulses from a frequency doubled Q-switched Nd:YAG laser are used. We employed 2 ns gated fast photography for studying the time evolution of the kernel at early times.
Bindhu, C V   +4 more
openaire   +3 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

An Investigation into Power from Pitch-Surge Point-Absorber Wave Energy Converters. [PDF]

open access: yes, 2007
There is a worldwide opportunity for clean renewable power. The results from the UK Government's "Marine Energy Challenge" showed that marine energy has the potential to become competitive with other forms of energy.
Chaplin, R. V.   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The mechanical characteristics of an aluminum foam winding CFRP composite structure under axial compression

open access: yesHeliyon
To enhance the energy absorption properties of the energy-absorbing structure, carbon fiber-reinforced polymer (CFRPs) with higher specific energy absorption and porous material aluminum foam with better compressive characteristics were organically ...
Hui Zhou   +3 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Exploding wire energy absorption dynamics at slow current rates [PDF]

open access: yes, 2017
Absorption of electrical energy provided to a metal wire in an exploding wire system is thought to be terminated or greatly diminished when the plasma is formed, after the joule heating of the metallic wire by the electrical current.
Rodriguez Prieto, G.   +2 more
core   +1 more source

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