Results 101 to 110 of about 3,937,771 (293)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Driving rural energy access: a second-life application for electric-vehicle batteries

Environmental Research Letters, 2014
Building rural energy infrastructure in developing countries remains a significant financial, policy and technological challenge. The growth of the electric vehicle (EV) industry will rapidly expand the resource of partially degraded, ‘retired’, but ...
Hanjiro Ambrose, Dimitry Gershenson, Alexander Gershenson, Daniel Kammen   +3 more
doaj   +1 more source

Electric Energy Access in Bangladesh

Transactions on Environment and Electrical Engineering, 2016
This paper represents the overall electrical energy profile and access in Bangladesh. In the recent past Bangladesh has been experiencing shortage of electricity, and about 42 % of population no access to the electricity. The electricity consumption has rapidly increased over last decade.
Muhammad Taheruzzaman, Przemyslaw Janik
openaire   +3 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

The political economy of gender mainstreaming in energy access in Sierra Leone

Environmental Research: Climate
In 2017, the Economic Community of West African States launched its Policy for Gender Mainstreaming in Energy Access with each member state tasked to create a National Action Plan (NAP).
Sarah Appiah, Victoria Plutshack, Mawunyo Agradi, Thomas W Klug, Isaac Nunoo, Rajah Saparapa   +5 more
doaj   +1 more source

NIGERIA’S ENERGY OPTIONS IN THE ERA OF CLIMATE CHANGE: AN ESSAY [PDF]

Journal of Sustainable Energy, 2020
Access to modern energy services is critical to realising a number of socioeconomic development challenges such as poverty eradication and improved health conditions.
DIOHA, M. O.
doaj  

Second-life battery systems for affordable energy access in Kenyan primary schools. [PDF]

Sci Rep, 2023
Kebir N, Leonard A, Downey M, Jones B, Rabie K, Bhagavathy SM, Hirmer SA.   +6 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

An empirical assessment of community energy injustice in Makueni, Kenya

Environmental Research: Energy
This paper used an empirical approach to understand how the actions and involvement of stakeholders such as government and the private sector contribute to energy injustice experienced by the community.
Sarah Odera, Jiska De Groot, Debbie Sparks, Dimitrios Mentis, Izael Da Silva   +4 more
doaj   +1 more source

Accurate intercensal estimates of energy access to track Sustainable Development Goal 7. [PDF]

EPJ Data Sci, 2022
Pokhriyal N, Letouzé E, Vosoughi S.
europepmc   +1 more source