Results 81 to 90 of about 34,307,861 (339)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
All-optical seasonal energy saving windows
iScienceSummary: Adaptive thermal regulation is crucial for year-round energy savings in buildings, especially in mid-latitude regions. Here, leveraging the seasonally varying angles of direct sunlight, we report a microprism-array sheet that enables seasonal ...
Beom-Su Kim +5 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Energy/Delay Tradeoffs in All-Spin Logic Circuits
IEEE Journal on Exploratory Solid-State Computational Devices and Circuits, 2016 All-spin logic (ASL) is a spin-based candidate for implementing logic in the next generation designs. The energy and the delay of ASL circuits are both inherently related to the geometric parameters of ASL gates, and the careful selection of the ...
Zhaoxin Liang, Sachin S. Sapatnekar
doaj +1 more source
European Energy Security: What Should It Mean? What to Do? ESF Working Paper, No. 23, 30 October 2006 [PDF]
, 2006 [From the Introduction]. • Is energy a strategic good? If it is, to what extent does it make sense to deny the extraction of political leverage from energy policy? In criticising Russian energy policy, are we not protesting too much against the fact that
Egenhofer, Christian, +4 more
core
Robust Worst-Case Analysis of Demand-Side Management in Smart Grids
, 2016 Demand-side management presents significant benefits in reducing the energy load in smart grids by balancing consumption demands or including energy generation and/or storage devices in the user's side. These techniques coordinate the energy load so that
Macua, Sergio Valcarcel +2 more
core +1 more source
Energy storage: The future enabled by nanomaterials
Science, 2019 Thinking small to store more From mobile devices to the power grid, the needs for high-energy density or high-power density energy storage materials continue to grow.
E. Pomerantseva +4 more
semanticscholar +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Holographic study of QQQ potential in a magnetic field background
Physics Letters BWe study triply heavy baryons in the presence of a magnetic field background using the AdS/CFT correspondence. The force balance equation, derived from the total action of triply heavy baryons, serves as the basis for calculating the separation distance ...
Jing Zhou, Xiaoling Leng
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source