Results 81 to 90 of about 8,436,065 (295)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Multiphysics Finite\u2013Element Modelling of an All\u2013Vanadium Redox Flow Battery for Stationary Energy Storage [PDF]
All-Vanadium Redox Flow Batteries (VRFBs) are emerging as a novel technology for stationary energy storage. Numerical models are useful for exploring the potential performance of such devices, optimizing the structure and operating condition of cell ...
Bertucco, Alberto +4 more
core +1 more source
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
The most general coordinates transformations that allow for the exact separation of the kinetic energy operator of a quantum many-body system into total center of mass kinetic energy and internal kinetic energy are found and discussed.
Fortunato, Lorenzo
core +1 more source
During flight birds navigate a dynamic atmospheric landscape which may add to or reduce the cost of flight if birds can exploit the atmosphere to their benefit. The atmospheric landscape is heavily influenced by the Earth’s surface and is therefore sensitive to landscape change and human development.
openaire +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Counting all the costs: recognising the carbon subsidy to polluting energy [PDF]
Excluding the cost of carbon pollution from decision-making creates market distortions and the undervaluation of emission reduction, argues this report.
core
Self-energy of electrons in critical fields [PDF]
The energy shift of K electrons in heavy atoms due to the self-energy correction has been calculated. This process is treated to all orders in Zα, where Z denotes the nuclear charge.
Greiner, Walter +3 more
core
Robust Worst-Case Analysis of Demand-Side Management in Smart Grids
Demand-side management presents significant benefits in reducing the energy load in smart grids by balancing consumption demands or including energy generation and/or storage devices in the user's side. These techniques coordinate the energy load so that
Macua, Sergio Valcarcel +2 more
core +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source

