Results 101 to 110 of about 22,054,072 (293)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Hybrid diesel generator/renewable energy system performance modeling
, 2014 Published ArticleA Hybrid Energy System may been defined as a system in which different energy sources (solar, wind, hydro, diesel generator, etc.) as well as energy storage systems are interconnected to meet the load energy demand at any time.
Vermaak, Herman Jacobus +1 more
core
, 2014 In declaring 2012 the international year of sustainable energy for all, the United Nations (UN) general assembly (2011) established at the personal initiative of the UN secretary general- three global ...
World Bank, International Energy Agency
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 1993 30 pages, 28 tables and 1 figure(sent upon request); text in Latex, report no.
openaire +2 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
A mechano-integrated gradient electrolyte for long-cycling solid-state lithium metal batteries
Nature CommunicationsOvercoming interfacial mechano-electrochemical failure remains a fundamental challenge in solid-state lithium metal batteries, where polymers offer conformal interfacial contact but suffer from low ionic conductivity, while oxides/sulfides provide high ...
Xiaoping Yi +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
All order merging of high energy and soft collinear resummation
SciPost Physics ProceedingsWe present a method of merging the exclusive LO-matched high energy resummation of High Energy Jets (HEJ) with the parton shower of PYTHIA which preserves the accuracy of the LO cross sections and the logarithmic accuracy of both resummation schemes ...
Jeppe R. Andersen, Hitham Hassan, Sebastian Jaskiewicz
doaj +1 more source