Results 91 to 100 of about 8,722,657 (381)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A systematic decision-making approach to optimizing microgrid energy sources in rural areas through diesel generator operation and techno-economic analysis: A case study of Baron Technopark in Indonesia

open access: yesInternational Journal of Renewable Energy Development
Microgrid systems are part of the most reliable energy supply technologies for rural communities that do not have access to electricity but the system is generally dominated by diesel generators (DG).
Adinda Prawitasari   +8 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Noether Symmetries and Covariant Conservation Laws in Classical, Relativistic and Quantum Physics

open access: yes, 2010
We review the Lagrangian formulation of Noether symmetries (as well as "generalized Noether symmetries") in the framework of Calculus of Variations in Jet Bundles, with a special attention to so-called "Natural Theories" and "Gauge-Natural Theories ...
Fatibene   +11 more
core   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Creep Behaviors of Methane Hydrate-Bearing Frozen Sediments

open access: yesEnergies, 2019
Creep behaviors of methane hydrate-bearing frozen specimens are important to predict the long-term stability of the hydrate-bearing layers in Arctic and permafrost regions.
Yanghui Li   +5 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Experimental Study of Spray Characteristics of Kerosene-Ethanol Blends from a Pressure-Swirl Nozzle

open access: yesInternational Journal of Aerospace Engineering, 2018
Partial replacement of kerosene by ethanol in a gas turbine is regarded as a good way to improve the spray quality and reduce the fossil energy consumption.
Tao Zhang   +5 more
doaj   +1 more source

Study on circuit breaker TRV issues of UHV high series compensation lines

open access: yesThe Journal of Engineering, 2019
Under the influence of series compensation (SC) capacitance and rated voltage rise, when ultra high voltage (UHV) high SC line occurs inner fault, the short-circuit current through the SC line is greater and the residual voltage across the SC is higher ...
Bin Zheng   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy