Results 41 to 50 of about 1,388,181 (313)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Energy loss of an energetic Ga ion in hot Au plasmas

Matter and Radiation at Extremes, 2016
Self-consistent calculations of energy loss for a Ga ion moving in hot Au plasmas are made under the assumption of wide ranges of the projectile energy and the plasma temperature with all important mechanisms considered in detail.
Bin He, Xujun Meng, Jianguo Wang
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Increase of the density, temperature and velocity of plasma jets driven by a ring of high energy laser beams

, 2013
Supersonic plasma outflows driven by multi-beam, high-energy lasers, such as Omega and NIF, have been and will be used as platforms for a variety of laboratory astrophysics experiments.
Fatenejad, M, Liang, EP, Park, HS, Fu, W, Lamb, DQ, Spitkovsky, Anatoly, Grosskopf, M, Remington, B   +7 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Clinical factors associated with trabecular bone score.

, 2013
Dual-energy X-ray absorptiometry (DXA) measurement of bone mineral density (BMD) is the reference standard for diagnosing osteoporosis but does not directly reflect deterioration in bone microarchitecture.
Hans, D., Leslie, W.D., Manitoba Bone Density, Program, Krieg, M.A.   +3 more
core   +1 more source

Minimum energy-maximum space:higher-density attached family housing [PDF]

, 2011
In 2016 all new houses in England and Wales must be zero carbon. To date most work in zero carbon housing has been carried out on detached family housing typologies.
Burford, N.K., Pearson, A. D., Thurrott, J.   +2 more
core   +1 more source

Time-resolved X-ray imaging of the current filamentation instability in solid-density plasmas

Nature Communications
The streaming of energetic charged particles can magnetize astrophysical and laboratory plasmas via the current filamentation instability. Despite its importance, the experimental characterization of this instability has remained a challenge.
Christopher Schoenwaelder, Alexis Marret, Stefan Assenbaum, Chandra B. Curry, Eric Cunningham, Gilliss Dyer, Stefan Funk, Griffin D. Glenn, Sebastian Goede, Dimitri Khaghani, Martin Rehwald, Ulrich Schramm, Franziska Treffert, Milenko Vescovi, Karl Zeil, Siegfried H. Glenzer, Frederico Fiuza, Maxence Gauthier   +17 more
doaj   +1 more source

Study on an Accurate Magnetic Network Model of Eccentric Magnet-Shaped Permanent Magnet Synchronous Motor

Applied Sciences
Permanent magnet synchronous motors (PMSMs) find extensive application across diverse domains thanks to their merits of high torque density and efficiency.
Tianle Li, Kai Yang, Fei Xiong, Cheng Luo, Zhihan Chen, Haiyang Hu, Tianxiang Liu   +6 more
doaj   +1 more source