Results 51 to 60 of about 1,052,656 (265)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A comparative study of bridged 1,2,4-oxazolones and their derivatives
Energetic Materials Frontiers, 2020 For energetic compounds, a slight difference in their molecular structures can result in a tremendous difference in their properties. Compounds with similar structures but exhibiting big difference in their physicochemical properties (such as density and
Teng Fei +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Tunable Plasmonic Bandwidth Broadening via DC Electrical Bias
NanomaterialsThe ability to broaden the bandwidth of nanodevices holds significant promise for applications in modern science and technology. In this work, we demonstrate a tunable approach to the bandwidth modulation of nanoresonators by applying a direct current ...
Chen Wei, Fuhua Gao, Fan Yang
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Dynamics of N5+-H electron capture in Debye plasmas
Matter and Radiation at Extremes, 2016 The electron capture in N5+-H collisions imbedded in a Debye plasma is studied by using the two-center atomic orbital close-coupling method in the energy range from 1 keV/u to 200 keV/u.
L. Liu, J.G. Wang
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Enhanced proton acceleration in an applied longitudinal magnetic field
New Journal of Physics, 2016 Using two-dimensional particle-in-cell simulations, we examine how an externally applied strong magnetic field impacts proton acceleration in laser-irradiated solid-density targets. We find that a kT-level external magnetic field can sufficiently inhibit
A Arefiev, T Toncian, G Fiksel
doaj +1 more source
Promoting Sustainable Mobility by Addressing Inequities in Electric Bike-Sharing Systems [PDF]
Journal of South Asian Logistics and TransportTransition to electric bike-sharing systems (EBSS) offers a sustainable and efficient solution for urban mobility, reducing emissions and enhancing accessibility. This study used data from New York City's bike-sharing program, combining socio-demographic
M. Mavin De Silva +3 more
doaj +1 more source