Results 111 to 120 of about 3,552,792 (348)
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Spatial features of CO2 for occupancy detection in a naturally ventilated school building
Accurate occupancy information helps to improve building energy efficiency and occupant comfort. Occupancy detection methods based on CO2 sensors have received attention due to their low cost and low intrusiveness.
Qirui Huang +3 more
doaj +1 more source
Distributed Control Strategy for Autonomous Operation of Hybrid AC/DC Microgrid
This paper proposes a distributed control strategy that considers several source characteristics to achieve reliable and efficient operation of a hybrid ac/dc microgrid. The proposed control strategy has a two-level structure.
Jongbok Baek, Wooin Choi, Suyong Chae
doaj +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Energy Efficiency Improvement Solutions for Supermarkets by Low-E Glass Door and Digital Semi-Hermetic Compressor [PDF]
Piyanut Saengsikhiao, Juntakan Taweekun
openalex +1 more source
The impact of the mushy zone parameter (Amushy) and the chosen numerical model during the solidification of a commercial paraffin-type phase change material (PCM) in a vertical cylinder under T-history conditions was examined through numerical ...
Milad Tajik Jamalabad +4 more
doaj +1 more source
Energy Efficiency: Efficiency or Monopsony? [PDF]
The cliché in the electricity sector, the "cheapest power plant is the one we don’t build," seems to neglect the benefits of the energy that plant would generate.
Timothy J. Brennan
core
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Energy Efficiency Economics and Policy [PDF]
Energy efficiency and conservation are considered key means for reducing greenhouse gas emissions and achieving other energy policy goals, but associated market behavior and policy responses have engendered debates in the economic literature.
Gillingham, Kenneth +2 more
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