Results 81 to 90 of about 12,146,561 (360)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Validation of black-box performance models for a water-to-water heat pump operating under steady state and dynamic loads [PDF]

open access: yesE3S Web of Conferences, 2019
The use of simple mathematical models for describing the behaviour of heat pumps is important for assessing the energy performance of this equipment when installed in buildings.
Fuentes Elena, Salom Jaume
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

ENERGY EFFICIENCY AS PRECONDITION OF ENERGY SECURITY

open access: yesJournal of Security and Sustainability Issues, 2015
Increase of energy efficiency remains as one of the major strategic objectives in Lithuania. Effective use of existing energy saving potential increases energy security and reduces emissions of greenhouse gas and other pollutants. In order to meet the growing energy demand and to reduce the negative impact of the energy sector on environment, increase ...
Baublys, Juozas   +3 more
openaire   +3 more sources

Application of Artificial Neural Networks for Virtual Energy Assessment

open access: yesEnergies, 2021
A Virtual energy assessment (VEA) refers to the assessment of the energy flow in a building without physical data collection. It has been occasionally conducted before the COVID-19 pandemic to residential and commercial buildings.
Amir Mortazavigazar   +6 more
doaj   +1 more source

Annual Report on Building Energy Management, Real Estate Asset Management, Fiscal Year 2015-2016 [PDF]

open access: yes, 2016
https://digitalcommons.memphis.edu/govpubs-tn-general-services-energy-efficiency-reports/1016/thumbnail ...
Tennessee. Department of General Services.
core   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Annual Report on Energy-Efficient Purchasing, Central Procurement Office, Fiscal Year 2018-2019 [PDF]

open access: yes, 2019
https://digitalcommons.memphis.edu/govpubs-tn-general-services-energy-efficiency-reports/1003/thumbnail ...
Tennessee. Department of General Services.
core   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Impact of Electric Vehicles Consumption on Energy Efficient and Self-Sufficient Performance in Building: A Case Study in the Brazilian Amazon Region

open access: yesEnergies
The growth of electric vehicles (EVs) and their integration into existing and future buildings bring new considerations for energy efficiency (EE) and balance when combined with renewable energy.
Ana Carolina Dias Barreto de Souza   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy