Results 81 to 90 of about 9,995,212 (291)

A triad framework for ship carbon reduction: Direct CO2 measurement, multi-intelligence fusion prediction, and Cauchy-enhanced speed optimization

Applied Ocean Research
Ship carbon emissions have become a global concern, yet significant challenges persist in precise quantification, real-time assessment, and operational optimization.
Xinxing Tan, Dehua Wang, Pu Sun, Tian Lan   +3 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Remarks about ship’s energy efficiency operational indicator [PDF]

, 2017
W artykule omówiono powody, dla których wyznacza się eksploatacyjny wskaźnik efektywności energetycznej statku. Podano jego definicję i określono, jakie dane wejściowe muszą być znane, aby można go było wyliczyć.
Herdzik, J.
core  

Impact of structural changes on energy efficiency of Finnish pulp and paper industry

, 2019
A key challenge in prevention of global warming is how to increase energy efficiency, to be able to deal with increased fossil CO2 emissions from rising energy usage.
Vakkilainen, Esa, Satu Kähkönen, Laukkanen, Timo, Esa Vakkilainen, Kähkönen, Satu, Timo Laukkanen   +5 more
core   +1 more source

Carbon Intensity Assessment of a Bulk Carrier Operating in Different Sea State Conditions

Journal of Marine Science and Engineering
This work uses the environmental contour line approach to estimate the long-term extremes of carbon emission generated by a bulk carrier operating in different sea state conditions, utilising short-term analyses of the ship propulsion energy efficiency ...
Yordan Garbatov, Petar Georgiev
doaj   +1 more source

Heat integration of ethanol and yeast manufacture

Macedonian Journal of Chemistry and Chemical Engineering, 2007
The increasing concern for the environmental impacts of human activities has stimulated the development of new methods for analysis of industrial processes and the implementation of energy conservation measures.
Aleksandar Anastasovski, Liljana Markovska, Vera Meshko   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Universal energy efficiency analysis models for integrated energy systems supporting multiple scenarios

Next Energy
Integrated Energy Systems (IESs) present complex structures and diverse operational scenarios that require sophisticated Integrated Energy Management Systems (IEMSs).
LILI YAO, LIANGWU XU, ZENGXU ZHAO
doaj   +1 more source