Results 41 to 50 of about 11,031,357 (308)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Applying ex post index decomposition analysis to final energy consumption for evaluating European energy efficiency policies and targets [PDF]

open access: yes, 2019
This paper aims to unravel the effects of both policies and autonomous developments driving the changes of final energy consumption for the European Union (EU28) and its member states complemented with an in-depth analysis of two EU member states ...
Sustainable Energy   +5 more
core   +1 more source

Experimental Research on the Room Air Conditioner with Thermoelectric Subcooler

open access: yesZhileng xuebao, 2016
In the vapor compression refrigeration system, the increasing subcooling degree of air conditioner can improve the refrigerating capacity and the coefficient of performance (COP).
Jin Tingxiang, L
doaj  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Improvement of Multi-functional Air-conditioning Water Heaters

open access: yesZhileng xuebao, 2015
An improved multi-functional air-conditioning water heater is devised to solve the problem of frequent starts and stops of fan, which always occurs while a traditional one produces hot water in summer. The improved multi-functional air-conditioning water
Wang Haifeng   +5 more
doaj  

Improving Energy Efficiency in Hotels Through Evolutionary Digital Twin Technology: A Conceptual Framework and Empirical Evidence

open access: yesBuildings
This study investigates the use of digital twin technology, machine learning (ML), and artificial intelligence (AI) to improve energy efficiency. It focuses on the heating, ventilation and air conditioning (HVAC) systems in hotel buildings which rely on ...
Rosana W. M. Wong, Becky P. Y. Loo
doaj   +1 more source

Fundamentals of Energy-Efficient Wireless Links: Optimal Ratios and Scaling Behaviors

open access: yes2024 IEEE 99th Vehicular Technology Conference (VTC2024-Spring)
In this paper, we examine the energy efficiency (EE) of a base station (BS) with multiple antennas. We use a state-of-the-art power consumption model, taking into account the passive and active parts of the transceiver circuitry, including the effects of radiated power, signal processing, and passive consumption.
Anders Enqvist   +3 more
openaire   +4 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Report of the Energy Efficiency Board. 2013.

open access: yes, 2014
Annual; Began with 2010; ceased with 2011.; At head of title: Connecticut Energy Efficiency ...
Connecticut. Energy Efficiency Board.
core   +1 more source

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