Results 61 to 70 of about 11,031,357 (308)

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Advantages of grass-grain crop rotations due to prolonged use of clover-alfalfa-timothy mixture

open access: yesАграрная наука Евро-Северо-Востока, 2020
It is known that significant saving of nitrogen fertilizers are due to perennial legume-cereal grasses use in crop rotations. From 2013 to 2018in the Mari El Republic six-field grass-grain fodder crop rotations were compared on sod-podzolic soils with a ...
A. K. Svechnikov
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Energy Efficiency Alberta TRM Introduction

open access: yes, 2020
This document is intended to provide a high-level understanding of the Energy Efficiency Alberta Technical Reference Manual (TRM), including background, how it was constructed, its intended use and general guidelines for maintenance and further ...
Energy Efficiency Alberta
core   +1 more source

Leasing-Based Performance Analysis in Energy Harvesting Cognitive Radio Networks

open access: yesSensors, 2016
In this paper, we consider an energy harvesting cognitive radio network (CRN), where both of primary user (PU) and secondary user (SU) are operating in time slotted mode, and the SU powered exclusively by the energy harvested from the radio signal of the
Fanzi Zeng, Jisheng Xu
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

National Action Plan for Energy Efficiency, Chapter 6: Energy Efficiency Program Best Practices

open access: yes, 2006
Chapter from the National Action Plan for Energy Efficiency documenting key findings from energy efficiency programs that have been successfully operating for many ...
National Action Plan for Energy Efficiency (U.S.)
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Promotion of Efficient Use of Energy: Final Report

open access: yes, 2006
The Department of Energy funded the Alliance to Save Energy to promote the efficient use of energy under a multiyear cooperative agreement. This funding allowed the Alliance to be innovative and flexible in its program development, and to initiate and ...
Alliance to Save Energy (U.S.)
core   +1 more source

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