Results 101 to 110 of about 1,149,935 (314)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

The energy efficiency of 8-bit low-power microcontrollers

open access: yes, 2011
We have measured the energy cost of processing, sleeping, non-volatile memory writes and ADC measurements of six 8-bit microprocessors from three manufacturers.
Jones, Mark Hedley, Scott, Jonathan B.
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Woodside Energy Ltd. Cossack Pioneer Facility Engineering Team

open access: yes, 2008
Cossack Pioneer is a floating production storage and offloading vessel located 112 km North West of Karratha. This report details the work performed during a 16 week internship with Woodside Energy Ltd working in the Cossack Pioneer Facility Engineering ...
Holmes, Julian
core  

Energy Storage Technologies for Smoothing Power Fluctuations in Marine Current Turbines [PDF]

open access: yes, 2012
With regard to marine renewable energies, significant electrical power can be extracted from marine tidal current. However, the power harnessed by a marine current turbine varies due to the periodicity of the tidal phenomenon and could be highly ...
CHARPENTIER, Jean-Frederic   +11 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Highlights of Industrial Energy Audits with Application in Paper Product Manufacturing

open access: yes, 1979
Experience in executing comprehensive energy audits in varied industrial plants has resulted in a basic audit methodology and has revealed several interesting energy conservation opportunities applicable to paper products manufacturing.
Hart, M. N., Bond, S. K.
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Energy production systems engineering

open access: yes, 2017
Energy Production Systems Engineering presents IEEE, Electrical Apparatus Service Association (EASA), and International Electrotechnical Commission (IEC) standards of engineering systems and equipment in utility electric generation stations.
Blair, Thomas Howard
core  

A self-powered and self-sensing knee negative energy harvester

open access: yesiScience
Summary: Wearable devices realize health monitoring, information transmission, etc. In this study, the human-friendliness, adaptability, reliability, and economy (HARE) principle for designing human energy harvesters is first proposed and then a ...
Daning Hao   +6 more
doaj   +1 more source

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