Results 81 to 90 of about 1,149,935 (314)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

An Introductory Energy Course to Promote Broad Energy Education for Undergraduate Engineering Students

open access: yes, 2021
Engineering graduates must be prepared to support our world’s need for a clean and sustainable energy future. Complex problems related to energy and sustainability require engineers to consider the broad spectrum of interrelated consequences including ...
Jan DeWaters   +2 more
core   +1 more source

Enhancing the European power system resilience with a recommendation system for voluntary demand response

open access: yesiScience
Summary: Climate change, geopolitical tensions, and decarbonization targets are bringing the resilience of the European electric power system to the forefront of discussion.
Carlos A.M. Silva   +9 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The use of alternative energy technologies in buildings: The influence of engineering consultants

open access: yes, 2006
This thesis was submitted for the degree of Engineering Doctorate and awarded by Brunel University, 26/05/2006.The UK Government has set the target of reducing CO2 emissions by 60% by 2050.
Cooke, Robert Stewart
core  

Capturing spatial effects, technology interactions, and uncertainty in urban energy and carbon models: Retrofitting Newcastle as a case-study [PDF]

open access: yes, 2012
08/10/12 MEB Author has confirmed its peer reviewedLocal authorities often rely upon urban energy and carbon modelling tools to develop mitigation policies and strategies that will deliver reductions in greenhouse gas emissions.
Calderon, C   +3 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Process Systems Engineering R&D for Advanced Fossil Energy Systems [PDF]

open access: yes, 2007
This presentation will examine process systems engineering R&D needs for application to advanced fossil energy (FE) systems and highlight ongoing research activities at the National Energy Technology Laboratory (NETL) under the auspices of a recently ...
Zitney, S. E.
core  

The Role of Nanofluids in Renewable Energy Engineering. [PDF]

open access: yesNanomaterials (Basel), 2023
Bhatti MM, Vafai K, Abdelsalam SI.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy