Results 111 to 120 of about 7,366,329 (309)

Spectrum of Clean Energy Innovation Fact Sheets

, 2011
In an effort to reduce the cost of biofuels, the National Renewable Energy Laboratory (NREL) has merged biochemistry with modern computing and mathematics.

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Characterization of growth and metabolism of the haloalkaliphile Natronomonas pharaonis [PDF]

, 2010
Natronomonas pharaonis is an archaeon adapted to two extreme conditions: high salt concentration and alkaline pH. It has become one of the model organisms for the study of extremophilic life.
Tanja Oberwinkler, Mendoza, Eduardo, Oesterhelt, Dieter, Ralf Zimmer, Dieter Oesterhelt, Pfeiffer Friedhelm, Orland Gonzalez, Oberwinkler Tanja, Zimmer, Ralf, Zimmer Ralf, Pfeiffer, Friedhelm, Oesterhelt Dieter, Mansueto, Locedie, Mendoza Eduardo, Gonzalez Orland, Mansueto Locedie, Gonzalez, Orland, Locedie Mansueto, Eduardo Mendoza, Oberwinkler, Tanja, Friedhelm Pfeiffer   +20 more
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Chemerin sustains the growth of spongiotrophoblast and sinusoidal trophoblast giant cells through fatty acid oxidation

BMC Biology
Background Placental metabolic dysfunction is associated with pregnancy complications, including preeclampsia, gestational diabetes mellitus, and fetal growth restriction.
Jia xuan Cai, Ai wen Le, Xin yue Han, Jie Chen, Xiao hua Lei, Chen Huang, Jian V. Zhang   +6 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Metabolism Regulation and Redox State: Insight into the Role of Superoxide Dismutase 1

, 2020
Energy metabolism and redox state are strictly linked; energy metabolism is a source of reactive oxygen species (ROS) that, in turn, regulate the flux of metabolic pathways.
Simona Damiano, Concetta Sozio, Paolo Mondola, Mariarosaria Santillo, Bruna Guida, Giuliana La Rosa, Raffaella Faraonio   +6 more
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NADPH Oxidase/Antioxidant Dual-Target Intervention Reduces Radiation-Induced Embryo Defects in Mice

Space: Science & Technology
The potential adverse effects of chronic exposure to extremely low doses of ionizing radiation on early mammalian embryonic development, particularly during the preimplantation stage, remains a topic of ongoing debate due to the lack of definitive ...
Chiyuan Ma, Qin Li, Yao Zhang, Yuxin Yang, Junru Wang, Dehong Li, Jingtong Xie, Yongfan Men, Yanan Li, Hailong Wang, Enkui Duan, Xiaohua Lei   +11 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

NREL Carbon Metabolism Modeling Intends to Make Biofuels Engineering Routine and Reliable (Fact Sheet)

, 2011
National Renewable Energy Laboratory (NREL) scientists, supported by the Department of Energy (DOE) Scientific Discovery through Advanced Computing (SciDAC) Program, have assembled and simulated a model of key eukaryotic carbon metabolism that intends to

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Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source