Results 141 to 150 of about 8,597,032 (385)

SOME EFFECTS OF ANTERIOR PITUITARY EXTRACTS ON NITROGEN METABOLISM, WATER BALANCE, AND ENERGY METABOLISM [PDF]

, 1933
O. H. Gaebler
openalex   +1 more source

Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

Nature Network Boston, 2020
Erik C.B. Johnson, E. Dammer, D. Duong, Lingyan Ping, Maotian Zhou, Luming Yin, L. Higginbotham, Andrew Guajardo, Bartholomew White, J. Troncoso, M. Thambisetty, T. Montine, Eddie B. Lee, J. Trojanowski, T. Beach, E. Reiman, V. Haroutunian, Minghui Wang, E. Schadt, Bin Zhang, D. Dickson, Nilufer Ertekin-Taner, T. Golde, V. Petyuk, P. D. De Jager, D. Bennett, T. Wingo, Srikant Rangaraju, I. Hajjar, J. Shulman, J. Lah, A. Levey, N. Seyfried   +32 more
semanticscholar   +1 more source

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

FEBS Open Bio, EarlyView.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He, Guiyi Gong, Geovani Quijas, Simon Ming‐Yuen Lee, Ratan K. Chaudhuri, Krzysztof Bojanowski   +5 more
wiley   +1 more source

Redox-mediated regulation of aging and healthspan by an evolutionarily conserved transcription factor HLH-2/Tcf3/E2A

Redox Biology, 2020
Physiological aging is a complex process, influenced by a plethora of genetic and environmental factors. While being far from fully understood, a number of common aging hallmarks have been elucidated in recent years.
Leonid Rozanov, Meenakshi Ravichandran, Giovanna Grigolon, Maria Clara Zanellati, Johannes Mansfeld, Kim Zarse, Nir Barzilai, Gil Atzmon, Fabian Fischer, Michael Ristow   +9 more
doaj  

Linking Fluorescence Spectroscopy and 31P MRS in NADH Phantoms [PDF]

arXiv
Glioblastoma exhibits significant metabolic alterations, making tracking energy metabolism important for its characterization. This could be crucial for glioblastoma resection in neurosurgery. We link two NADH monitoring methods, showing linear dependence on phantom concentrations.
arxiv  

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Lactate: the ugly duckling of energy metabolism

Nature Metabolism, 2020
J. Rabinowitz, S. Enerbäck
semanticscholar   +1 more source

The Regulatory Role and Mechanism of Energy Metabolism in Vascular Diseases

Frontiers in Bioscience-Landmark
Vascular diseases are amongst the most serious diseases affecting human life and health globally. Energy metabolism plays a crucial role in multiple vascular diseases, and the imbalance of energy metabolism in cells from the blood vessel wall can cause ...
Taoli Sun, Wei Yuan, Yu Wei, Duanfang Liao, Qinhui Tuo   +4 more
doaj   +1 more source

Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria

FEBS Open Bio, EarlyView.
The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao, Takato Ozaki, Hirofumi Fukuda, Yu Kanesaki, Munehiko Asayama   +4 more
wiley   +1 more source

Positive feedback loop between MAPK and aquaporin 7 regulates autophagy and apoptosis induced by palmitate in RIN‐m5f cells

FEBS Open Bio, EarlyView.
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang, Jiang Tan, Xueting He, Yuqin Chen, Guoping Qiu, Mei Yang   +5 more
wiley   +1 more source