Results 91 to 100 of about 2,110,233 (290)

Temperature stability of intersubband transitions in AlN/GaN quantum wells

, 2010
Temperature dependence of intersubband transitions in AlN/GaN multiple quantum wells grown with molecular beam epitaxy is investigated both by absorption studies at different temperatures and modeling of conduction-band electrons.
Andersson, Thorvald G., Berland, Kristian, Farivar, Rashid, Hyldgaard, Per, Larsson, Anders, Stattin, Martin, Sultan, D. M. S., Wang, Shu Min   +7 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Accelerating the transition to cobalt-free batteries: a hybrid model for LiFePO4/graphite chemistry

npj Computational Materials
The increased adoption of lithium-iron-phosphate batteries, in response to the need to reduce the battery manufacturing process’s dependence on scarce minerals and create a resilient and ethical supply chain, comes with many challenges.
Gabriele Pozzato, Xueyan Li, Donghoon Lee, Johan Ko, Simona Onori   +4 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Predictive Modeling of River Water Temperatures in Catu River: A Neural Network-Based Approach

Applied Computational Intelligence and Soft Computing
Predicting water temperature (Tw) in tropical environments is crucial for ecosystem monitoring and the sustainable management of water resources. Highly accurate and reliable Tw forecasts are essential for the ecological management of rivers.
Carmen Goncalves de Macedo e Silva, José Roberto de Araújo Fontoura, Alarcon Matos de Oliveira, Thais de Souza Neri, Roberto Luiz Souza Monteiro, Thiago Barros Murari, Alexandre do Nascimento Silva, Leandro Brito Santos, Marcos Batista Figueredo   +8 more
doaj   +1 more source

Carbon-tax implementation in Indonesia: a social accounting matrix analysis

Sustainability: Science, Practice, & Policy
As the adverse effects of climate change intensify, numerous countries are making several efforts to reduce their carbon-dioxide (CO2) emissions. One of the widely adopted strategies is the implementation of a carbon tax.
Luthfiana Rahma, Djoni Hartono, Sasmita Hastri Hastuti   +2 more
doaj   +1 more source

Energy and Economic Analysis for Greenhouse Ground Insulation Design

Energies, 2018
Energy and life cycle cost analysis were employed to identify the most-cost effective ground envelope design for a greenhouse that employs supplemental lighting located in Ottawa, Ontario, Canada (45.4° N). The envelope design alternatives that were
James Bambara, Andreas K. Athienitis
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source