Results 81 to 90 of about 2,110,233 (290)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
HAEC-SIM: A Simulation Framework for Highly Adaptive Energy-Efficient Computing Platforms
EAI Endorsed Transactions on Energy Web, 2016 This work presents a new trace-based parallel discrete event simulation framework designed for predicting the behavior of a novel computing platform running energy-aware parallel applications.
Mario Bielert +4 more
doaj +1 more source
Models for High-Energy Processes [PDF]
Reviews of Modern Physics, 1970 Recent developments in the concepts and models used to describe high-energy collisions of fundamental particles are reviewed. The areas of appreciable activity in research in high-energy physics are surveyed briefly and the general framework for the description of processes at high energies is outlined.
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Modeling the Energy Performance of LoRaWAN
Sensors, 2017 LoRaWAN is a flagship Low-Power Wide Area Network (LPWAN) technology that has highly attracted much attention from the community in recent years. Many LoRaWAN end-devices, such as sensors or actuators, are expected not to be powered by the electricity ...
Lluís Casals +3 more
doaj +1 more source
Modeling of the youBot in a serial link structure using twists and wrenches in a bond graph [PDF]
, 2010 We present a walk-through tutorial on the modeling of a complex robotic system, like the newly developed desktop mobile manipulator youBot developed by KUKA[5, 4].
Breedveld, Peter +4 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Breaks and Trends in OECD Countries’ Energy-GDP Ratios [PDF]
This paper uses the econometrics of endogenous structural breaks to examine changes in energy intensity for OECD countries over 1960-2009. Nearly all OECD countries currently have significant negatively trending energy-GDP ratios; but for several ...
Liddle, Brantley
core +1 more source
Time-dependent Stochastic Modeling of Solar Active Region Energy
, 2010 A time-dependent model for the energy of a flaring solar active region is presented based on a stochastic jump-transition model (Wheatland and Glukhov 1998; Wheatland 2008; Wheatland 2009).
A.O. Benz +40 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source