Results 51 to 60 of about 223,481 (265)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
On the conjecture of Sombor energy of a graph
Examples and Counterexamples, 2023 The Sombor matrix of a graph G with vertices v1,v2,…,vnis defined as ASO(G)=[sij], where sij=di2+dj2if viis adjacent to vjand sij=0, otherwise, where diis the degree of a vertex vi.
Harishchandra S. Ramane +1 more
doaj +1 more source
The energy of a tripartite graph
AIP Conference Proceedings, 2019 The energy of a graph is used to approximate the total π-electron energy of molecules. Thus, finding a new technique that facilitates this task is a challenge that has received increased research attention. This paper introduces the eigenvalues of a complete tripartite graph Ti,i,n-2i, for n ≥ 4, with respect to the adjacency, Laplacian, and signless ...
Alawn, Nawras A. +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Some New Results on Various Graph Energies of the Splitting Graph
Journal of Chemistry, 2019 The energy of a simple connected graph G is equal to the sum of the absolute value of eigenvalues of the graph G where the eigenvalue of a graph G is the eigenvalue of its adjacency matrix AG.
Zheng-Qing Chu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Some degree-based topological indices and (normalized Laplacian) energy of graphs [PDF]
Discrete Mathematics Letters, 2022 Zimo Yan, Xie Zheng, Jianping Li
doaj +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source