Results 71 to 80 of about 22,779,738 (260)

Implementation of repowering optimization for an existing photovoltaic-pumped hydro storage hybrid system: A case study in Sichuan, China [PDF]

, 2019
Summary For a remote area or an isolated island, where the grid has not extended, a standalone hybrid energy system can provide cheap and adequate power for local users.
Lund, Henrik, Xu, Xiao, Cao, Di, Hu, Weihao, Sustainable Energy Supply Systems, Energy System Analysis, Chen, Zhe; id_orcid, Energy and Resources, Chen, Zhe, Liu, Wen   +9 more
core   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Competing uses of biomass for energy and chemicals: Implications for long-term global CO2 mitigation potential [PDF]

, 2015
Biomass is considered a low carbon source for various energy or chemical options. This paper assesses it’s different possible uses, the competition between these uses, and the implications for long-term global energy demand and energy system emissions. A
Faaij, André, Daioglou, Vasileios, Energy System Analysis, Wicke, Birka, Energy and Resources, van Vuuren, Detlef, Environmental Sciences   +6 more
core   +1 more source

Developing a Techno-Economic Framework for National-Level End-State Decarbonisation Resource Analysis: A UK Application

Energies
Amid growing urgency for net-zero delivery and calls for simplified energy system modelling, this study presents a techno-economic framework, termed “End-state Decarbonisation Resource Analysis” (EDRA), for evaluating national decarbonisation strategies.
Lin Gao, Philip Naylor, Abdelrahman Hegab, Pericles Pilidis   +3 more
doaj   +1 more source

Belgian Energy Transition: What Are the Options?

Energies, 2020
Different scenarios at different scales must be studied to help define long term policies to decarbonate our societies. In this work, we analyse the Belgian energy system in 2035 for different carbon emission targets, and accounting for electricity, heat,
Gauthier Limpens, Hervé Jeanmart, Francois Maréchal   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Power Generation Time Series for Solar Energy Generation: Modelling with ATlite in South Africa

Solar
The global energy landscape is experiencing growing challenges, with energy crises in regions such as South Africa underscoring the drive to accelerate the shift toward renewable energy solutions.
Nicolene Botha, Toshka Coleman, Gert Wessels, Maximilian Kleebauer, Stefan Karamanski   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source