Results 81 to 90 of about 136,814 (309)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Investigating 100% renewable energy supply at regional level using scenario analysis
International Journal of Sustainable Energy Planning and Management, 2016 Energy modelling work in Ireland to date has mainly taken place at a national level. A regional modelling approach is necessary however, for Ireland to reach the ambitious targets for renewable energy and emissions reduction.
Annicka Waenn +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Surrogate models for composed simulation models in energy systems [PDF]
Energy Informatics, 2018 Abstract New technologies and methodologies for smart grid applications cannot be tested in the real power grid, since it is a safety-critical infrastructure, therefore simulation and co-simulation is utilized. Simulation models itself can rely on quite complex calculations and therefore slow down the simulation.
openaire +2 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
An Investigation on Energy Recovery Analysis of Active Suspension System [PDF]
, 2013 Currently active suspension system is more applicable than passive for improving the suspension performance, ensuring the stability and passenger safety in modern automotive suspension system.
Gu, Fengshou +7 more
core
, 2022 Utilizing solar energy for heat supply can reduce CO2 emissions and mitigate global climate change. In the Nordic region (e.g., Iceland and Finland), a tremendous seasonal mismatch exists between the availability of solar radiation and building heating ...
Hirvonen, Janne +6 more
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Belgian Energy Transition: What Are the Options?
Energies, 2020 Different scenarios at different scales must be studied to help define long term policies to decarbonate our societies. In this work, we analyse the Belgian energy system in 2035 for different carbon emission targets, and accounting for electricity, heat,
Gauthier Limpens +2 more
doaj +1 more source