Results 41 to 50 of about 323,837 (316)

Assessment of Grid and System Supportability Based on Spatio-Temporal Conditions—Novel Key Performance Indicators for Energy System Evaluation

Energies
The energy transition introduces new technical standards, laws and regulations regarding the stability and reliability of energy grids and systems. Due to the non-existence of a measuring standard, key performance indicators (KPIs) were developed to ...
Heiko Waurisch, Nick von Bargen, Nico Ploczicki, Bente Ralfs, Berit Elsner, Reiner Schütt, Nassipkul Dyussembekova   +6 more
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

The Technical and Economic Aspects of Using DC or AC Motors in the Drive of Hoisting Machines

Energies
A hoisting machine is one of the main components of an underground mine process line. The drive systems currently used in these machines are based on direct current, synchronous, or induction (AC) motors. Power electronic converters are used to power and
Tomasz Siostrzonek, Jacek Pytel, Tomasz Karpiel   +2 more
doaj   +1 more source

Households’ Energy Transformation in the Face of the Energy Crisis

Energies, 2023
The purpose of conducted research was to recognize factors determining households’ Energy transition and barriers that slow that process. Energy transition itself, understood as a shift in the structure of fuels used in energy production and technological changes related to its use, are key elements of shaping the economy.
Elżbieta Jadwiga Szymańska, Maria Kubacka, Jan Polaszczyk   +2 more
openaire   +2 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

The Research Progress of Monoclonal Antibody Labeled with 89Zr

Journal of Isotopes
Zirconium-89 (89Zr) is a metallic positron-emitting radionuclide. The relatively long half-life and moderate energy making 89Zr especially suitable for the labeling of large biomolecules such as antibodies for radioimmuno-PET (positron emission ...
Zhanxiong XIAO, Fei DUAN, Hongyu LI
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, Volume 19, Issue 7, Page 1918-1934, July 2025.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Meteorological conditions during periods of low wind speed and insolation in Germany: The role of weather regimes

Meteorological Applications, 2023
Renewable power generation from wind and solar energy is strongly dependent on the weather. To plan future sustainable energy systems that are robust to weather variability, a better understanding of why and when periods of low wind and solar power ...
Fabian Mockert, Christian M. Grams, Tom Brown, Fabian Neumann   +3 more
doaj   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Green energy and steel imports reduce Europe’s net-zero infrastructure needs

Nature Communications
Importing renewable energy to Europe may offer many potential benefits, including reduced energy costs, lower pressure on infrastructure development, and less land use within Europe.
Fabian Neumann, Johannes Hampp, Tom Brown   +2 more
doaj   +1 more source