Results 121 to 130 of about 8,375,210 (301)
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Determining recorder distances from multicopters to avoid bat disturbance
IntroductionThis study examines the impact of two multicopters, differing in size and weight (ConVecDro hexacopter, DJI Mavic 2 Pro quadcopter), on the activity of bats assigned to three distinct echolocation groups.
Marc Huamán Roswag +4 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
The increasing integration of renewable energy sources, smart appliances, and distributed energy technologies has significantly increased the complexity of residential energy systems, necessitating advanced Home Energy Management Systems (HEMS ...
Md Mamun Ur Rashid +4 more
doaj +1 more source
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Calibrated Physics-Based Dynamic Energy Modelling of an Airport Terminal
This study developed a calibrated, data-supported energy simulation model for the Arrivals Terminal of Cluj-Napoca International Airport (Romania), addressing challenges in modelling complex building typologies.
Ancuța Maria Măgurean, Dan Doru Micu
doaj +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
We quantify in more detail than earlier studies the cost trade-offs of establishing import-export links between Europe and North Africa for two quintessential energy carriers needed for the energy transition: electricity and hydrogen.
Francesco Dalla Longa, Bob van der Zwaan
doaj +1 more source

