Results 101 to 110 of about 2,959,388 (279)

Optimization of Well Locations and Trajectories: Comparing Sub-Vertical, Sub-Horizontal and Multi-Lateral Well Concepts for Marginal Geothermal Reservoir in The Netherlands

open access: yesEnergies
Scaling up the direct use of geothermal heat in urban areas comes with the challenge of enabling the development of projects in geological settings where geothermal reservoir flow properties may be poor, resulting in low well flow performance.
Eduardo G. D. Barros   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Aggregation of Distributed Energy Resources and Energy Storage Systems in Active Distribution Networks: A Critical Review

open access: yesEnergies
The transition of modern power systems is going through the challenges of uncertainties originating from equipment unavailability, forecasting errors, market fluctuations, prosumer behaviors, regulatory and policy changes, and extreme weather conditions.
Pranta Dash Gupta   +3 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Energy Recovery From Polluted Water Using Capacitive Deionization Desalination System: A Review

open access: yesIEEE Access
Capacitive deionization is used to purify water by applying an electric charge across two porous electrodes. These electrodes are positioned in a spacer channel that transports the desalinated water.
Md Sazal Miah   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Probabilistic Resilience Enhancement of Active Distribution Networks Against Wildfires Using Hybrid Energy Storage Systems

open access: yesApplied Sciences
Wildfires pose significant threats to the resilience of distribution systems. Furthermore, the phenomenon of global warming is further intensifying their contribution to power outages.
Muhammad Usman Aslam   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Transient and Steady-State Evaluation of Distributed Generation in Medium-Voltage Distribution Networks

open access: yesEnergies
As power generation systems with increasingly higher capacities are interconnected with distribution networks, a pressing need arises for a thorough analysis of their integration and the subsequent impacts on medium-voltage lines.
Daniel Guillén-López   +3 more
doaj   +1 more source

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