Results 21 to 30 of about 614,636 (258)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Evaluation method and module design for cost-effective compliance with irradiance guidelines to maintain soil quality in solar parks

open access: yesEPJ Photovoltaics
Ground mounted solar parks lead to changes in the micro-climate under and between the PV tables. In particular, the vegetation on the soil is, in various degrees, shaded from direct sunlight and indirect, diffuse light. Also, the changes in precipitation
Cesar Ilkay, Van Aken Bas B.
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

From Retrofitting to Renewables: Navigating Energy Transition Pathways for European Residential Space Heating

open access: yesEnergies
Transformative actions are crucial across all sectors emitting greenhouse gases. Nonetheless, energy transition research to date displays a notable imbalance, with a larger emphasis on the supply side than on the demand side.
Steven S. Salim   +3 more
doaj   +1 more source

Continuous multi-column sorption-enhanced dimethyl ether synthesis (SEDMES): Dynamic operation

open access: yesFrontiers in Chemical Engineering, 2023
In this work the continuous production of dimethyl ether (DME) by sorption-enhanced DME synthesis (SEDMES) technology has been demonstrated for the first time with a multi-column test-rig. A continuous single-pass carbon yield up to 95%, higher than ever
Jasper van Kampen   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Differences between economical, ecological and societal optimal designs of solar parks due to feed-in restrictions

open access: yesEPJ Photovoltaics
With increasing market share of distributed, renewable electricity generation, challenges like net congestion, become increasingly relevant. Solar parks in northwest Europe are generating electrical energy homogeneously over the full capacity range.
Van Aken Bas B., Cesar Ilkay
doaj   +1 more source

Exploring Model-Based Decarbonization and Energy Efficiency Scenarios with PROMETHEUS and TIAM-ECN

open access: yesEnergies, 2023
This study provides a quantitative analysis of future energy–climate developments at the global level using two well-established integrated assessment models (IAMs), PROMETHEUS and TIAM-ECN.
Panagiotis Fragkos   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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