Results 31 to 40 of about 835,140 (307)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

WE ENERGY GAME: PROMOTING GAME-BASED LEARNING AS AN INNOVATIVE STRATEGY TO EDUCATE ON ENERGY TRANSITION

open access: yes, 2019
Sustainability has become an important blueprint to achieve a better future for all, and as part of this process, nations are called to accelerate an energy transition towards clean energy solutions.
Wim J.L. Elving   +5 more
core   +1 more source

From Retrofitting to Renewables: Navigating Energy Transition Pathways for European Residential Space Heating

open access: yesEnergies
Transformative actions are crucial across all sectors emitting greenhouse gases. Nonetheless, energy transition research to date displays a notable imbalance, with a larger emphasis on the supply side than on the demand side.
Steven S. Salim   +3 more
doaj   +1 more source

Exploring Model-Based Decarbonization and Energy Efficiency Scenarios with PROMETHEUS and TIAM-ECN

open access: yesEnergies, 2023
This study provides a quantitative analysis of future energy–climate developments at the global level using two well-established integrated assessment models (IAMs), PROMETHEUS and TIAM-ECN.
Panagiotis Fragkos   +5 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Differences between economical, ecological and societal optimal designs of solar parks due to feed-in restrictions

open access: yesEPJ Photovoltaics
With increasing market share of distributed, renewable electricity generation, challenges like net congestion, become increasingly relevant. Solar parks in northwest Europe are generating electrical energy homogeneously over the full capacity range.
Van Aken Bas B., Cesar Ilkay
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Modelling complexity in the energy transition

open access: yes, 2021
Over the years, it has become clearer and clearer: the energy transition is taking shape. Research on the energy transition also evolves. In the TPM Energy Transition Lab, we aim to take an interdisciplinary approach to expand our knowledge on ‘what ...
Chappin, E.J.L. (author)
core  

From energy consumers to prosumers—how do policies influence the transition?

open access: yes, 2021
Active producer-consumers (prosumers) still number relatively few in most countries, excluding frontrunner countries such as Germany and the USA, where small-scale solar power generation by property-owners has made strong inroads.
Saari, Ulla A.,   +9 more
core   +1 more source

Home - About - Disclaimer - Privacy