Results 31 to 40 of about 58,780,734 (168)

Validación del minimental Parkinson en el deterioro cognitivo de la enfermedad de Parkinson

open access: yes, 2006
La enfermedad de Parkinson (EP) es un trastorno neurodegenerativo en el que predominan los síntomas motores; sin embargo, con la progresión de la enfermedad se evidencia un deterioro cognitivo, que para ser detectado requiere la utilización de tests ...
Coronel Oquendo, Ana Paulina
core   +1 more source

Caracterización funcional y calidad de vida en pacientes con enfermedad de Parkinson en un hospital de tercer nivel de Bogotá D.C., Colombia

open access: yesRevista Colombiana de Medicina Física y Rehabilitación, 2020
Introducción. La enfermedad de Parkinson es considerada la segunda enfermedad neurodegenerativa que más genera discapacidad motora y neuropsiquiátrica; es un trastorno de causa multifactorial cuyo síntoma cardinal es la bradicinesia, seguida de temblor,
Sandra Bibiana Avendaño-Avendaño   +2 more
doaj   +1 more source

Neuropsychiatric Adverse Events Associated With Foslevodopa/Foscarbidopa Continuous Subcutaneous Infusion in Clinical Practice: A Multicenter Study

open access: yesEuropean Journal of Neurology, Volume 33, Issue 7, July 2026.
In 214 patients with advanced Parkinson's disease receiving foslevodopa/foscarbidopa continuous subcutaneous infusion, neuropsychiatric adverse events occurred in 19.2%. Baseline cognitive impairment and hallucinations did not increase risk, whereas preexisting impulse control disorders predicted ICD‐related adverse events.
David Campo‐Caballero   +130 more
wiley   +1 more source

Factors linked to informal caregiver burden in dementia across Latin America and the Caribbean: A systematic review and meta‐analysis

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Informal caregivers are central to dementia care in Latin America and the Caribbean (LAC), yet determinants of caregiver burden remain insufficiently characterized. We conducted a systematic review and meta‐analysis of studies examining patient‐ and caregiver‐related correlates of burden in LAC.
Paula Quintero‐Cardona   +5 more
wiley   +1 more source

Enfermedad de Parkinson: estrategias terapéuticas disponibles

open access: yes, 2023
Parkinson\u27s disease is a complex chronic neurodegenerative disorder. Although a cure against it is not yet available, there are several therapeutic means that help controlling the symptomatology manifestations during its progression.
Latorre-Barragán, , Fernanda   +3 more
core   +2 more sources

Medidas psicométricas de la escala de rango cognitiva para la enfermedad de Parkinson (PDCRS) evaluada en pacientes con enfermedad de Parkinson que asistieron a la consulta externa de neurología del Hospital Carlos Andrade Marín entre marzo y mayo del 2009

open access: yes, 2009
La enfermedad de Parkinson (EP) es un desorden neurodegenerativo crónico, progresivo, caracterizado por síntomas motores y no motores (1). Para el diagnóstico de la Demencia en Parkinson se ha desarrollado una escala que ayuda a diagnosticar defectos ...
Villena Chica, Diana Elizabeth   +1 more
core   +1 more source

Factors associated with the quality of life of subjects with Parkinson's disease and burden on their caregivers

open access: yesNeurología (English Edition), 2015
Introduction: Parkinson's disease affects the quality of life of the individual with the disease in addition to creating a burden on the caregiver. Factors related to these effects include motor and non-motor aspects of the disease, as well as traits ...
M. Rodríguez-Violante   +4 more
doaj   +1 more source

Mitochondrial Transplantation as a New Therapeutic Approach Against Cardiac and Renal Consequences in Male Rats With Myocardial Infarction

open access: yesActa Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim Myocardial infarction (MI) is one of the leading causes of death worldwide. MI is associated with cardiac structural and functional alterations. Among these, cardiac fibrosis may be significantly influenced by mitochondrial dysfunction. We sought to evaluate whether the injection of functional mitochondria from healthy muscle could improve
María Cuesta‐Corral   +13 more
wiley   +1 more source

Caracterización de los pacientes con enfermedad de Parkinson

open access: yesActa Médica del Centro, 2021
Introducción: la enfermedad de Parkinson es un proceso degenerativo complejo del sistema nervioso central de inicio insidioso progresivo y desarrollo lento que es consecuencia de una lesión idiopática en el sistema extrapiramidal.
Lázaro Aurelio Vázquez Gómez   +3 more
doaj  

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

open access: yesAdvanced Science, Volume 13, Issue 28, 18 May 2026.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman   +15 more
wiley   +1 more source

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