Results 41 to 50 of about 1,043 (175)

Genética de la enfermedad de Parkinson

Revista de Neuro-Psiquiatría, 2013
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Cosentino, C., Mazzetti, P.
openaire   +2 more sources

Detection of TDP‐43 seeds in CSF of presymptomatic and symptomatic genetic FTD/ALS

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION Seed amplification assays (SAAs) have shown promising results in detecting misfolded transactive response (TAR) DNA‐binding protein 43 (TDP‐43) in cerebrospinal fluid (CSF) of genetic frontotemporal dementia (FTD). To date, the use of SAA has yet to be evaluated in presymptomatic individuals.
Ilaria Linda Dellarole, Vittoria Aprea, Marcella Catania, Claudia Battipaglia, Aurora Romeo, Cristina Villa, Anna Burato, Luigi Celauro, Eleonora Dalla Bella, Nilo Riva, Erika Salvi, Giacomina Rossi, Giuseppe Di Fede, Giuseppe Legname, Julie F H De Houwer, Antonella Alberici, Barbara Borroni, Harro Seelaar, John C van Swieten, Fabio Moda, Paola Caroppo   +20 more
wiley   +1 more source

Musicoterapia en enfermedad de Parkinson

Voices: A World Forum for Music Therapy, 2008
Este trabajo presenta los resultados de la experiencia de intervención musicoterapéutica en pacientes con Parkinson del Servicio de Medicina Física y Rehabilitación del Instituto Nacional de Geriatría de Santiago de Chile.
openaire   +2 more sources

Beta Power Response After Levodopa Intake in Parkinson's Disease Patients With Chronic Sensing‐Enabled Deep Brain Stimulation

Annals of Neurology, Volume 98, Issue 6, Page 1352-1363, December 2025.
Objective In Parkinson's disease (PD), the power of beta oscillations (± 13–30 hertz [Hz]) from subthalamic nucleus (STN) local field potentials (LFPs) is associated with motor symptoms. Beta power can be used for adaptive deep brain stimulation (aDBS) algorithms based upon symptom fluctuations.
Martijn G.J. de Neeling, Bart J. Keulen, Mariëlle J. Stam, Deborah Hubers, Rob M.A. de Bie, Bernadette C.M. van Wijk, P. Rick Schuurman, Arthur W.G. Buijink, Martijn Beudel   +8 more
wiley   +1 more source

Microglial CLEC7A restrains amyloid beta plaque pathology in a mouse model of Alzheimer's disease

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION CLEC7A is a surface receptor that is highly upregulated on microglia in many Alzheimer's disease (AD) models. Little is known about the role that microglial CLEC7A signaling plays in AD‐related pathogenesis. METHODS We utilized an inducible, central nervous system (CNS) macrophage‐specific knockout of Clec7a to evaluate the role ...
Aman Mangalmurti, Kristine E. Zengeler, Ava Hollis, Emily Golden, Gabrielle Riddlemoser, John R. Lukens   +5 more
wiley   +1 more source

Asociación inversa entre consumo de tabaco y enfermedad de Parkinson idiopática

Anales del Sistema Sanitario de Navarra, 2009
Se lleva a cabo la evaluación del efecto del consumo de tabaco durante el periodo de la vida entre los 20 y 50 años de edad, y la enfermedad de Parkinson idiopática, en un estudio caso-control realizado en Navarra. Se observa una asociación inversa: para
R. Larumbe, J.J. Viñes, F. Guillén, I. Gaminde, M.T. Artázcoz   +4 more
doaj   +1 more source

Predicting medical prognosis in patients with glioblastoma during inpatient rehabilitation using bed mobility function

PM&R, Volume 17, Issue 11, Page 1343-1353, November 2025.
Abstract Background Determining appropriate suitability and goals for inpatient rehabilitation of patients with glioblastoma, isocitrate dehydrogenase‐wildtype (GBM) requires real‐time prognostic information. Functional measures, such as bed mobility, are standardized scores that can be assessed by members of the care team at the bedside and may aid ...
Tomasz Gruchala, Christopher W. Lewis, Kathryn Abplanalp, Prakash Jayabalan, Theresa L. Walunas, Jodi L. Johnson, Derek A. Wainwright, Rimas V. Lukas, Gayle Spill, Ishan Roy   +9 more
wiley   +1 more source

Six Drivers of Aging Identified Among Genes Differentially Expressed With Age

Aging Cell, Volume 24, Issue 11, November 2025.
A meta‐analysis of 25 transcriptomic datasets from mammalian tissues revealed 45 genes consistently upregulated or downregulated with age. Orthologs of these genes were functionally evaluated using Caenorhabditis elegans lifespan screens to reveal those with causal roles in the aging process, thus identifying six evolutionarily conserved drivers of ...
Ariella Coler‐Reilly, Zachary Pincus, Erica L. Scheller, Roberto Civitelli   +3 more
wiley   +1 more source

Terapia celular “neuro-restauradora” en la enfermedad de Parkinson: un debate pendiente

Anales del Sistema Sanitario de Navarra, 2008
Existe en la actualidad un gran entusiasmo sobre las perspectivas derivadas de la denominada terapia celular en la enfermedad de Parkinson. Este entusiasmo ha sobrepasado la esfera de la comunidad médica, llegando hasta el público general, y se ha venido
J.L. Lanciego, N. Gonzalo, M.C. Rodríguez-Oroz, M. Rodríguez, J.A. Obeso   +4 more
doaj   +1 more source

Neuropatía Periférica en la enfermedad de Parkinson

Revista de Neuro-Psiquiatría, 2021
La enfermedad de Parkinson es una entidad neurodegenerativa con alteraciones principalmente extrapiramidales, del sistema nervioso autónomo y, en etapas finales, alteraciones cognitivas y neuropsiquiátricas. Desde 1976 se reconocen además síntomas neurosensoriales dependientes del sistema nervioso periférico, presentes en casi la mitad de los pacientes
openaire   +3 more sources