Results 11 to 20 of about 19,693 (199)
Mediators of Inflammation, 2013 Tumoral necrosis factor α plays a central role in both the inflammatory response and that of the immune system. Thus, its blockade with the so-called anti-TNF agents (infliximab, etanercept, adalimumab, certolizumab pegol, and golimumab) has turned into ...
Daniel Sánchez-Cano +4 more
doaj +2 more sources
Journal of Osteoporosis, 2015 Glucocorticoids (GCs) are the cornerstone of the therapy in many autoimmune and inflammatory diseases. However, it is well known that their use is a double edged sword, as their beneficial effects are associated almost universally with unwanted effects ...
Miguel Ortego-Jurado +6 more
doaj +2 more sources
Permeabilidad intestinal y enfermedades autoinmunes [PDF]
, 2016 Universidad de Sevilla.
Franco García, María del Carmen
openaire +4 more sources
Uncovering Genetic Variation in Systemic Lupus Erythematosus Risk Variants in Indigenous Peruvians. [PDF]
ACR Open RheumatolObjective Systemic lupus erythematosus (SLE) results in worse clinical outcomes among individuals of Amerindian descent. The genetic basis for this is uncertain, and there is a significant lack of genetic research focused on Amerindian ancestry populations.
Lanata CM +9 more
europepmc +2 more sources
Arthritis &Rheumatology, Volume 75, Issue 6, Page 984-995, June 2023., 2023 Objective The present study was undertaken to longitudinally evaluate titers of antibodies against β2‐glycoprotein I (anti‐β2GPI) and domain 1 (anti‐D1), to identify predictors of variations in anti‐β2GPI and anti‐D1 titers, and to clarify whether antibody titer fluctuations predict thrombosis in a large international cohort of patients who were ...
Cecilia B. Chighizola +92 more
wiley +1 more source
TFAM-deficient mouse skin fibroblasts – an ex vivo model of mitochondrial dysfunction
Disease Models & Mechanisms, 2021 Mitochondrial dysfunction associates with several pathological processes and contributes to chronic inflammatory and ageing-related diseases. Mitochondrial transcription factor A (TFAM) plays a critical role in maintaining mtDNA integrity and function ...
Manuel J. Del Rey +7 more
doaj +1 more source
La importancia del laboratorio en el diagnóstico del síndrome de Sjögren primario
Revista de la Facultad de Ciencias Médicas de Córdoba, 2009 El síndrome de Sjögren (SS) es una enfermedad autoinmune sistémica que se caracteriza fundamentalmente por la presencia de xeroftalmía y xerostomía debido a la infiltración de las glándulas lagrimales y salivares por células linfoplasmocitarias. Al igual
Pilar Brito-Zerón +6 more
doaj +1 more source
Global excellence in rheumatology in Latin America: The case of systemic lupus erythematosus
Frontiers in Medicine, 2023 Systemic lupus erythematosus (SLE) affects more severely non-White populations, due to their genetic background and sociodemographic characteristics.
Manuel F. Ugarte-Gil +9 more
doaj +1 more source
, 2022 JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 20, Issue 9, Page 1228-1230, September 2022.
Ines Bertlich +5 more
wiley +1 more source
Necrotizing Sarcoid Granulomatosis: A Disease Not to be Forgotten
Case Reports in Medicine, Volume 2020, Issue 1, 2020., 2020 Sarcoidosis is a systemic granulomatous disease of unknown aetiology characterised by the appearance of noncaseifying epithelioid granulomas in the affected organs, most commonly the lungs, skin, and eyes (Iannuzzi et al. 2007). Necrotizing Sarcoid Granulomatosis (NGS) is a rare and little‐known form of disease, which also presents nodular lung lesions,
A. I. Parejo-Morón +6 more
wiley +1 more source