Results 41 to 50 of about 10,787 (237)

Comparison of regional blood flow values measured by radioactive and fluorescent microspheres [PDF]

, 2002
Fluorescent microspheres (FM) have become an attractive alternative to radioactive microspheres (RM) for the measurement of regional blood flow (RBF). The aim of the present study was to investigate the comparability of both methods by measuring RBF with
Habler, O., Harris, A. G., Kleen, M., Meisner, F., Messmer, K., Raab, S., Thein, E.   +6 more
core   +1 more source

Pharmacologic pitfalls in heart failure: A guide to drugs that may cause or exacerbate heart failure. A European Journal of Heart Failure expert consensus document

European Journal of Heart Failure, Volume 27, Issue 12, Page 2671-2690, December 2025.
Main categories of harmful drugs in heart failure. CCB, calcium channel blocker; DPP4i, dipeptidyl peptidase‐4 inhibitor; HER2‐TT, human epidermal growth factor receptor 2‐targeted therapy; NSAID, non‐steroidal anti‐inflammatory drug; TKI, tyrosine kinase inhibitor; TZD, thiazolidinedione; VEGF Inh, vascular endothelial growth factor inhibitor.
Amr Abdin, Johann Bauersachs, Magdy Abdelhamid, Suleman Aktaa, Hussam Al Ghorani, Antonio Bayes‐Genis, Jan Biegus, Michael Böhm, Javed Butler, Nicolas Girerd, Marco Metra, Wilfried Mullens, Hadi Skouri, Muthiah Vaduganathan, Seif El Hadidi, Giuseppe M.C. Rosano, Gianluigi Savarese   +16 more
wiley   +1 more source

Unconscious auditory information-processing during general anaesthesia [PDF]

, 1992
This dissertation aims to examine the possibility of cognitive processing and memory storage in anaesthesia. It consists of four parts. The first section provides a brief outline of unconscious mental processes in psychological research.
Jelicic, M. (Marko)
core   +4 more sources

Acute-on-chronic Liver Failure: MELD Score 30-day Mortality Predictability and Etiology in a Pakistani Population [PDF]

, 2020
Background: Cirrhosis is a pathological condition that ultimately leads to liver failure. Acute on chronic liver failure (ACLF) has a high short term mortality rate. Viral hepatitis is the most common cause of liver failure in our local population.
Gilani, N. A. (Naeem), Khalid, T. (Talha), Sarfraz, A. (Azza), Sarfraz, M. (Muzna), Sattar, S. (Saim), Siddiq, J. (Javaria)   +5 more
core  

Use of Drugs With Actionable Pharmacogenetic Biomarkers and Possible Prescribing Changes Among Older People

Journal of the American Geriatrics Society, Volume 73, Issue 12, Page 3679-3689, December 2025.
This graphical abstract illustrates the annual prevalence of exposure to CPIC Level A drugs among older adults, categorized by type of pharmacogenetic recommendation. Data are presented per 1000 older individuals (A) and per 1000 prescriptions (B).
Zinan Zhao, Yuxuan Zhao, Xiaowen Hu, Xue Wang, Gengchen Wang, Xinyi Zhang, Wenliang Dong, Luwen Shi, Xiaodong Guan, Christine Y. Lu, Pengfei Jin, Xiaoyan Nie   +11 more
wiley   +1 more source

Pharmacogenomic testing and its future in community pharmacy [PDF]

, 2020
Although it is common to see pharmacogenomic testing used North America and Australia, it is not yet part of practice in the UK. With the promise of genomic screening becoming part of the NHS, pharmacists must equip themselves with a knowledge of how the
Wright, David, Youssef, Essra
core   +1 more source

Bidirectional Relationship Between Anaesthetic Drugs and Metabolic Syndrome: Clinical Effects and Mechanisms

Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT Metabolic syndrome (MS) is a multifaceted condition characterised by insulin resistance, dyslipidemia, central obesity and hypertension, significantly elevating the risks of cardiovascular diseases and type 2 diabetes. This review aims to elucidate the bidirectional interplay between anaesthetic agents and MS, highlighting the mutual influence
Yuying Huang, Qinghai Lan, Yijian Chen, Youchun Li, Baolin Zhong, Yuxin Zhan, Simin Deng   +6 more
wiley   +1 more source

Characterizing optogenetically mediated rebound effects in anaesthetized mouse primary visual cortex

The Journal of Physiology, Volume 603, Issue 16, Page 4609-4636, 15 August 2025.
Abstract figure legend Many studies of cortical circuits use optogenetic activation of inhibitory interneurons to suppress pyramidal cell activity, but after the light is turned off pyramidal cells sometimes show excess spiking, which is called a post‐inhibitory rebound.
Jared T. Shapiro, Nicole M. Michaud, Nathan A. Crowder   +2 more
wiley   +1 more source

Effect of intravenous anesthetic propofol on synaptic vesicle exocytosis at the frog neuromuscular junction [PDF]

, 2014
Aim: To investigate the presynaptic effects of propofol, a short-acting intravenous anesthetic, in the frog neuromuscular junction. Methods: Frog cutaneous pectoris nerve muscle preparations were prepared.
Fonseca, Matheus de Castro, Gomez, Marcus Vinicius, Gomez, Renato Santiago, Guatimosim, Cristina, Leite, Luciana Ferreira   +4 more
core   +1 more source

Vasopressin‐Sensitive Aqp2 Regulation Mediated by the TAZ‐NR4A1 Axis in Renal Collecting Duct Cells

The FASEB Journal, Volume 39, Issue 13, 15 July 2025.
The TAZ‐NR4A1 axis was identified as a critical regulator of vasopressin‐induced AQP2 expression, essential for water homeostasis. Conditional TAZ‐knockout mice showed polyuria and a significant decrease in AQP2 expression in collecting ducts. In mpkCCDc11 cells, TAZ knockdown significantly impaired vasopressin‐mediated AQP2 expression independently of
Hong Seok Choi, Hyo‐Ju Jang, Wan‐Young Kim, Sun Ah Park, Euijung Park, Hyun Jun Jung, Tae‐Hwan Kwon   +6 more
wiley   +1 more source