Results 21 to 30 of about 3,104 (195)

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen   +11 more
wiley   +1 more source

Manuseio de grave diminuição de hemoglobina em paciente jovem, testemunha de Jeová, submetido à proctocolectomia total: relato de caso Manoseo de grave disminución de hemoglobina en paciente joven, testigo de Jehová, sometido a la proctocolectomia total: relato de caso Extreme intraoperative hemodilution in Jehovah’s witness patient submitted total proctocolectomy: case report

open access: yesRevista Brasileira de Anestesiologia, 2005
JUSTIFICATIVA E OBJETIVOS: Os riscos de transfusão homóloga de sangue são bem conhecidos e alguns pacientes recusam esta transfusão por motivos religiosos.
Luiz Eduardo Imbelloni   +3 more
doaj   +1 more source

French‐Speaking Network of Pharmacogenetics (RNPGx) Recommendations for Gene Panel Analysis Through Genotyping or Sequencing in Pharmacogenetics

open access: yesFundamental &Clinical Pharmacology, Volume 40, Issue 1, January 2026.
ABSTRACT Background The implementation of pharmacogenetics in clinical practice increasingly relies on multigene panels. Objectives The objective of this study is to develop harmonized recommendations for the design and analytical implementation of multigene pharmacogenetic panels, defining clinically relevant genes and associated regions of interest ...
Nicolas Picard   +29 more
wiley   +1 more source

Pharmacologic pitfalls in heart failure: A guide to drugs that may cause or exacerbate heart failure. A European Journal of Heart Failure expert consensus document

open access: yesEuropean Journal of Heart Failure, Volume 27, Issue 12, Page 2671-2690, December 2025.
Main categories of harmful drugs in heart failure. CCB, calcium channel blocker; DPP4i, dipeptidyl peptidase‐4 inhibitor; HER2‐TT, human epidermal growth factor receptor 2‐targeted therapy; NSAID, non‐steroidal anti‐inflammatory drug; TKI, tyrosine kinase inhibitor; TZD, thiazolidinedione; VEGF Inh, vascular endothelial growth factor inhibitor.
Amr Abdin   +16 more
wiley   +1 more source

Conformational exploration of enflurane in solution and in a biological environment

open access: yes, 2015
Enflurane is a fluorinated volatile anesthetic, whose bioactive conformation is not known. Actually, a few studies have reported on the conformations of enflurane in nonpolar solution and gas phase.
Stephens, Susanna L.   +7 more
core   +2 more sources

Use of Drugs With Actionable Pharmacogenetic Biomarkers and Possible Prescribing Changes Among Older People

open access: yesJournal of the American Geriatrics Society, Volume 73, Issue 12, Page 3679-3689, December 2025.
This graphical abstract illustrates the annual prevalence of exposure to CPIC Level A drugs among older adults, categorized by type of pharmacogenetic recommendation. Data are presented per 1000 older individuals (A) and per 1000 prescriptions (B).
Zinan Zhao   +11 more
wiley   +1 more source

Bidirectional Relationship Between Anaesthetic Drugs and Metabolic Syndrome: Clinical Effects and Mechanisms

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT Metabolic syndrome (MS) is a multifaceted condition characterised by insulin resistance, dyslipidemia, central obesity and hypertension, significantly elevating the risks of cardiovascular diseases and type 2 diabetes. This review aims to elucidate the bidirectional interplay between anaesthetic agents and MS, highlighting the mutual influence
Yuying Huang   +6 more
wiley   +1 more source

Characterizing optogenetically mediated rebound effects in anaesthetized mouse primary visual cortex

open access: yesThe Journal of Physiology, Volume 603, Issue 16, Page 4609-4636, 15 August 2025.
Abstract figure legend Many studies of cortical circuits use optogenetic activation of inhibitory interneurons to suppress pyramidal cell activity, but after the light is turned off pyramidal cells sometimes show excess spiking, which is called a post‐inhibitory rebound.
Jared T. Shapiro   +2 more
wiley   +1 more source

Effect of Enflurane on the Baroreflex Control of Heart Rate in Decerebrate Rats

open access: yes, 2004
Volatile anesthetics alter the arterial baroreflex (BRX) but its mechanisms are poorly understood. This study was designed to determine the effect of 1 and 2 minimal alveolar concentrations (MAC) of enflurane on the BRX parameters in unanesthetized brain
남상범   +4 more
core   +1 more source

Summary of Clinical Research on Acupuncture Anesthesia in Combination with General Anesthesia of Enflurane Inhalation for Resection of Esophageal Carcinoma

open access: yes针刺研究, 2001
Objective: To observe the clinical effect of acupuncture anethesia in combination with general anesthesia of enflurane for radical operation of esophageal carcinoma.
尹志礼   +5 more
doaj  

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