Results 11 to 20 of about 3,104 (195)

Enflurane [PDF]

open access: yesAnaesthesia and Intensive Care, 2007
Enflurane is a halogenated ether used as an anesthetic. This structure has been used in an introductory organic/biochemistry course to illustrate how the basic structure of an ether has been modified to produce a less flammable, but still effective ...
C, Ball, R N, Westhorpe
core   +4 more sources

Enflurane Additive for Sodium Negative Electrodes. [PDF]

open access: yesACS Appl Mater Interfaces, 2022
Development of sodium anodes, both hard carbon (HC) and metallic, is dependent on the discovery of electrolyte formations and additives able to stabilize the interphase and support Na+ transport.
Akkisetty B   +5 more
europepmc   +3 more sources

Pharmacokinetics and safety of prolonged paracetamol treatment in neonates: An interventional cohort study

open access: yesBritish Journal of Clinical Pharmacology, Volume 89, Issue 11, Page 3421-3431, November 2023., 2023
Aims To investigate the pharmacokinetics and safety of prolonged paracetamol use (>72 h) for neonatal pain. Methods Neonates were included if they received paracetamol orally or intravenously for pain treatment. A total of 126 samples were collected. Alanine aminotransferase and bilirubin were measured as surrogate liver safety markers. Paracetamol and
Sissel Haslund‐Krog   +12 more
wiley   +1 more source

Effects of N2O elimination on the elimination of second gases in a two‐step mathematical model of heterogeneous gas exchange

open access: yesPhysiological Reports, Volume 11, Issue 21, November 2023., 2023
Effects of N2O elimination on the elimination of second gases in a two‐step mathematical model of heterogeneous gas exchange. Abstract We have investigated the elimination of inert gases in the lung during the elimination of nitrous oxide (N2O) using a two‐step mathematical model that allows the contribution from net gas volume expansion, which occurs ...
Ben Korman   +2 more
wiley   +1 more source

Repurposing ketamine to treat cocaine use disorder: integration of artificial intelligence‐based prediction, expert evaluation, clinical corroboration and mechanism of action analyses

open access: yesAddiction, Volume 118, Issue 7, Page 1307-1319, July 2023., 2023
Abstract Background and aims Cocaine use disorder (CUD) is a significant public health issue for which there is no Food and Drug Administration (FDA) approved medication. Drug repurposing looks for new cost‐effective uses of approved drugs. This study presents an integrated strategy to identify repurposed FDA‐approved drugs for CUD treatment.
Zhenxiang Gao   +6 more
wiley   +1 more source

Cross-approximate entropy of cortical local field potentials quantifies effects of anesthesia - a pilot study in rats

open access: yesBMC Neuroscience, 2010
Background Anesthetics dose-dependently shift electroencephalographic (EEG) activity towards high-amplitude, slow rhythms, indicative of a synchronization of neuronal activity in thalamocortical networks. Additionally, they uncouple brain areas in higher
Schwarz Cornelius   +5 more
doaj   +1 more source

PKQuest: volatile solutes – application to enflurane, nitrous oxide, halothane, methoxyflurane and toluene pharmacokinetics

open access: yesBMC Anesthesiology, 2002
Background The application of physiologically based pharmacokinetic models (PBPK) to human studies has been limited by the lack of the detailed organ information that is required for this analysis.
Levitt David G
doaj   +1 more source

Long noncoding RNA H19 knockdown promotes angiogenesis via IMP2 after ischemic stroke. [PDF]

open access: yesCNS Neurosci Ther
Downregulation of H19 enhances angiogenesis and mitigates BBB damage by regulating IMP2, thereby alleviating cerebral I/R injury. Abstract Aims This study aimed to explore the effects of long noncoding RNA (lncRNA) H19 knockdown on angiogenesis and blood–brain barrier (BBB) integrity following cerebral ischemia/reperfusion (I/R) and elucidate their ...
Zhong L   +9 more
europepmc   +2 more sources

Interaction between Artificial Membranes and Enflurane, a General Volatile Anesthetic: DPPC-Enflurane Interaction

open access: yes, 2003
The structural modifications of the dipalmitoylphosphatidylcholine (DPPC) organization induced by increasing concentration of the volatile anesthetic enflurane have been studied by differential scanning calorimetry, small-angle, and wide-angle x-ray ...
Artzner, Franck   +8 more
core   +1 more source

Early Activation of Children Operated on under Extracorporeal Circulation

open access: yesОбщая реаниматология, 2008
Objective: to study the safety and clinical and economic efficiency of early activation of children operated on under extracorporeal circulation (EC). Subjects and methods.
P. R. Dudov, I. A. Kozlov
doaj   +1 more source

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