Results 121 to 130 of about 3,347,961 (297)
Values and Vision: Perspectives on Philanthropy in 21st Century China [PDF]
, 2017 Values and Vision: Perspectives on Philanthropy in 21st Century China is an exploratory study of philanthropic giving among China's very wealthy citizens.
Paula D. Johnson, Tony Saich
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Engaged Leadership: New Concept or Evolutionary in Nature? [PDF]
, 2012 Mr. Woods provides a critique and a book review of Clint Swindall‘s Engaged Leadership. His accolades relate primarily to Swindell‘s communication of connecting the dynamics of a work environment and the applications of engaged leadership in fable format.
Woods, Edward, III
core +2 more sources
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Engaged learning in MOOCs: a study using the UK Engagement Survey
, 2015 This study sets out to answer the question: how can we know what learning is taking place in MOOCs? From this starting point, the study then looks to identify MOOCs’ potential for future use in HE?
Davis, Hugh C. +2 more
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For Community-Engaged Work, Isabel Clark ’19 Honored as 2018 Newman Civic Fellow [PDF]
, 2018 For her work undertaking real-world projects that solve critical needs for local communities, Isabel Clark has been honored as a 2018 Newman Civic Fellow, a national award recognizing a select group of student leaders who create lasting change in ...
Rodrigues, Jill
core +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source